INTESTINE Vol.13 No.3(2-4)


特集名 colitic cancer診断update
題名 2. 診断 (4) NBIによる潰瘍性大腸炎のサーベイランス
発刊年月 2009年 05月
著者 樋田 信幸 兵庫医科大学内科学下部消化管科
著者 松本 譽之 兵庫医科大学内科学下部消化管科
【 要旨 】 潰瘍性大腸炎(ulcerative colitis;UC)の長期経過症例は,大腸癌発生の高危険群である.癌およびdysplasiaを早期に発見するための定期的なsurveillance colonoscopy(SC)が推奨されており,最近では新しい内視鏡診断法を駆使した狙撃生検によるSCの有用性が示されてきている.Narrow Band Imaging(NBI)は,色素散布が不要で簡便に画像強調が行える方法であるため,UCのSCへの応用が期待されている.UC合併腫瘍のSCに対するNBIの臨床的有用性について,現在までの知見をまとめ,その可能性と問題点について述べる.
Theme Update in management of colitic cancer
Title Colonoscopic surveillance for ulcerative colitis using Narrow Band Imaging
Author Nobuyuki Hida Division of Lower Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine
Author Takayuki Matsumoto Division of Lower Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine
[ Summary ] Patients with long-standing extensive ulcerative colitis (UC) are at increased risk of developing colitis associated colorectal cancer. Annual surveillance colonoscopy has been recommended to properly diagnose neoplastic lesions in such patients. Recently, a new surveillance strategy with targeted biopsies, employing novel endoscopic techniques, has been implemented to efficiently detect neoplasia. Narrow Band Imaging (NBI) is a novel, convenient optical image-enhanced technique, which does not require dye spraying. It can be used for surveillance colonoscopy in patients with UC. We review recent findings on the clinical usefulness of NBI for neoplasia screening in UC patients, and discuss the advantages and limitations of this method.
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