| 特集名 | LSTの最前線 | |
|---|---|---|
| 題名 | LSTに対する分子病理学・遺伝子学的アプローチ (1) 他の肉眼型腫瘍との比較 | |
| 発刊年月 | 2006年 09月 | |
| 著者 | 藤井 茂彦 | 京都大学大学院医学研究科消化器内科学 |
| 著者 | 武川 賢一郎 | 獨協医科大学病理学 (人体分子) |
| 著者 | 吉竹 直人 | 獨協医科大学病理学 (人体分子) |
| 著者 | 千葉 勉 | 京都大学大学院医学研究科消化器内科学 |
| 著者 | 藤盛 孝博 | 獨協医科大学病理学 (人体分子) |
| 【 要旨 】 | 要旨はありません。 | |
| Theme | Update on laterally spreading tumor (LST) | |
|---|---|---|
| Title | Genetic characterizations of laterally spreading tumors compared to other macroscopic types of colorectal tumors | |
| Author | Shigehiko Fujii | Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine |
| Author | Kenichiro Mukawa | Department of Surgical and Molecular Pathology, Dokkyo University School of Medicine |
| Author | Naoto Yoshitake | Department of Surgical and Molecular Pathology, Dokkyo University School of Medicine |
| Author | Tsutomu Chiba | Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine |
| Author | Takahiro Fujimori | Department of Surgical and Molecular Pathology, Dokkyo University School of Medicine |
| [ Summary ] | Laterally spreading tumors (LST) have been classified as those lesions larger than 10 mm in diameter and extending circumferentially rather than vertically. They are classified into two subtypes : granular (LST-G) and non granular (LST-NG). However, they are not clearly defined at present. We analyzed the molecular biological features of LSTs compared to other macroscopic types of colorectal tumors (protruded type I, superficial elevated type IIa and IIa + IIc, depressed type IIc and IIa). These results suggest that LSTs should be classified as an independent disease entity. In our study, LST-Gs are similar to the protruded type of tumor and some aspects of LST-NGs are similar to depressed type tumors. However, other aspects of LST-NGs are similar to those of the protruding type tumor. |
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