Theme |
Serrated polyp of the colon, including large hyperplastic polyp |
Title |
Large hyperplastic polyp of the colorectum : relationship between large hyperplastic polyp and colorectal cancer |
Author |
Yasushi Sano |
Gastointestinal Center, SANO Hospital |
Author |
Tomonori Yano |
Division of Endoscopy, National Cancer Hospital East |
Author |
Kuang-I Fu |
Department of Radiology, Dokkyo Medical University |
Author |
Takahiro Fujii |
Takahiro Fujii Clinic |
[ Summary ] |
Hyperplastic polyps of the colorectum has been generally small, diminutive, predominantly left side colon, and considered benign lesion. Large HPs (>10 mm in size) were rare. Recently it was reported that some of large HPs were associated with synchronous carcinoma and had a potential of developing to carcinoma. In this review, we described the data that genetic alternations were observed in many cases of LHPs. We suggest that LHPs was the entity that need to remove in clinical practice. |