| 特集名 | 大腸腫瘍治療後のサーベイランス | |
|---|---|---|
| 題名 | 中間期癌（interval cancer）について | |
| 発刊年月 | 2018年 07月 | |
| 著者 | 草場 喜雄 | 久留米大学医学部内科学講座消化器内科部門／久留米大学医学部消化器病センター |
| 著者 | 鶴田 修 | 久留米大学医学部内科学講座消化器内科部門／久留米大学医学部消化器病センター |
| 著者 | 永田 務 | 久留米大学医学部内科学講座消化器内科部門／久留米大学医学部消化器病センター |
| 著者 | 徳安 秀紀 | 久留米大学医学部内科学講座消化器内科部門／久留米大学医学部消化器病センター |
| 著者 | 大内 彬弘 | 久留米大学医学部内科学講座消化器内科部門／久留米大学医学部消化器病センター |
| 著者 | 向笠 道太 | 久留米大学医学部内科学講座消化器内科部門／久留米大学医学部消化器病センター |
| 【 要旨 】 | 過去5年以内などの比較的短い期間内に癌検査がなされていたにもかかわらず発見された癌を中間期癌と呼んでいる．現在，大腸癌における中間期癌の定義は統一されていない．WEO（World Endoscopy Organization）の定義では「癌の指摘がなかったスクリーニングまたはサーベイランス検査後の推奨された期間を空けた次の検査前までに発見された癌」とされているが，その明確な期間の設定はない．中間期癌の発生率は検診の精度，精検（大腸内視鏡検査など）の受検率にも大きく関係してくるため，中間期癌発生率減少に向けての今後の対策は，大腸癌早期発見，早期治療と密接に関連し，大腸癌死亡率の減少につながっていくと考える． | |
| Theme | Surveillance after Treatment for Colorectal Tumors | |
|---|---|---|
| Title | Characteristics of Interval Colorectal Cancer | |
| Author | Yoshio Kusaba | Division of Gastroenterology, Division of GI Endoscopy, Department of Medicine, Kurume University School of Medicine / Division of Endoscopy, Kurume University School of Medicine |
| Author | Osamu Tsuruta | Division of Gastroenterology, Division of GI Endoscopy, Department of Medicine, Kurume University School of Medicine / Division of Endoscopy, Kurume University School of Medicine |
| Author | Tsutomu Nagata | Division of Gastroenterology, Division of GI Endoscopy, Department of Medicine, Kurume University School of Medicine / Division of Endoscopy, Kurume University School of Medicine |
| Author | Hidenori Tokuyasu | Division of Gastroenterology, Division of GI Endoscopy, Department of Medicine, Kurume University School of Medicine / Division of Endoscopy, Kurume University School of Medicine |
| Author | Akihiro Ouchi | Division of Gastroenterology, Division of GI Endoscopy, Department of Medicine, Kurume University School of Medicine / Division of Endoscopy, Kurume University School of Medicine |
| Author | Michita Mukasa | Division of Gastroenterology, Division of GI Endoscopy, Department of Medicine, Kurume University School of Medicine / Division of Endoscopy, Kurume University School of Medicine |
| [ Summary ] | Interval colorectal cancer is defined as an invasive cancer that is diagnosed using another test within the next fiscal year after a negative immunochemical fecal occult blood test (iFOBT) result. Any cancers that are diagnosed within 1 year of a negative screening result or after a positive screening result, wherein further investigation yielded a negative result or was refused, are classified as interval cancers. Few studies have reported on interval colorectal cancer in individuals undergoing screening based on iFOBT. We investigated the characteristics of interval colorectal cancer among participants of an iFOBT screening program. Interval colorectal cancer showed characteristic features with respect to sex, age, location, and stage. Compared with positive cancers, interval cancers were significantly more likely to be of higher stage and involve the cecum. A higher proportion of patients with metastatic lesions were present in the interval group than in the positive cancer group. Annual screening is effective for reducing the incidence of interval cancers, and interventions to promote continuous participation in screenings are required. For valid comparison among various areas or facilities, it is necessary to unify the operational definition and analytical methods of interval cancer. |
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