臨牀消化器内科 Vol.33 No.3(4-3)


特集名 GERD診療2018―現状と課題
題名 GERDの治療(3)外科治療
発刊年月 2018年 03月
著者 小熊 潤也 東海大学医学部消化器外科
著者 小澤 壯治 東海大学医学部消化器外科
著者 数野 暁人 東海大学医学部消化器外科
著者 新田 美穂 東海大学医学部消化器外科
著者 二宮 大和 東海大学医学部消化器外科
著者 谷田部 健太郎 東海大学医学部消化器外科
【 要旨 】 内科的治療に不応なGERDや食道裂孔ヘルニアを合併したGERD患者に対して,胃食道逆流を防止する外科治療が選択される場合がある.現在は低侵襲な腹腔鏡下手術が主流で,噴門形成の方法は胃底部を腹部食道に270°巻き付けるToupet法が多くの施設で行われている.近年,24時間食道インピーダンス,pHモニタリングにより胃食道逆流の評価がより精緻になり,GERDのより具体的な手術適応基準の確立が望まれるとともに,欧米や本邦で臨床研究が進められている,より低侵襲な逆流防止法である内視鏡的治療についても,その有効性や長期成績の評価が待たれる.
Theme GERD in Clinical Practice 2018 -- Current Status and Issues
Title Surgical Treatment for GERD
Author Junya Oguma Department of Gastroenterological Surgery, Tokai University School of Medicine
Author Soji Ozawa Department of Gastroenterological Surgery, Tokai University School of Medicine
Author Akihito Kazuno Department of Gastroenterological Surgery, Tokai University School of Medicine
Author Miho Nitta Department of Gastroenterological Surgery, Tokai University School of Medicine
Author Yamato Ninomiya Department of Gastroenterological Surgery, Tokai University School of Medicine
Author Kentaro Yatabe Department of Gastroenterological Surgery, Tokai University School of Medicine
[ Summary ] Surgical treatment to prevent/control gastroesophageal reflux is often selected for patients with gastroesophageal reflux disease (GERD) who are refractory to medical treatment or present with concomitant severe hiatal hernia symptoms. Laparoscopic surgery using the Toupet fundoplication technique is the procedure most commonly performed in hospitals to treat these patients and involves rolling the fornix around the abdominal esophagus at an angle of 270 degrees. Recently, detailed evaluation of gastroesophageal reflux has been facilitated by the introduction of 24‒hour esophageal impedance and pH monitoring. Thus, it would be possible to establish more objective criteria to aid patient selection for the surgical management of GERD. Clinical trials to evaluate endoscopic treatment for the management of GERD are underway in Western countries, as well as in Japan. These are minimally invasive antireflux procedures, and their usefulness and long‒term outcomes need to be evaluated in the future.
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