臨牀消化器内科 Vol.33 No.10(4-4)


特集名 十二指腸上皮性非乳頭部腫瘍の診療を巡って ― 現状と課題
題名 十二指腸上皮性非乳頭部腫瘍の診断を巡って (4) 浸水下EMR
発刊年月 2018年 09月
著者 井上 俊太郎 大阪国際がんセンター消化管内科
著者 山崎 泰史 岡山大学病院消化器内科
著者 上堂 文也 大阪国際がんセンター消化管内科
【 要旨 】 表在性非乳頭部十二指腸腫瘍(superficial nonampullary duodenal epithelial tumors;SNADETs)に対する内視鏡治療は,十二指腸の解剖学的な特徴により偶発症が問題となる.内視鏡的粘膜切除術(EMR)や粘膜下層剥離術(ESD),cold snare polypectomy(CSP)が行われているが,治療の標準化に至っていない.われわれは10~20mmのSNADETsに対する治療として浸水下EMR(UEMR)が有用と考え実践しており,治療の概説を行った.
Theme Diagnosis and Treatment of Non-ampullary Duodenal Epithelial Tumor -- Current Status and Issues
Title Underwater Endoscopic Mucosal Resection
Author Shuntaro Inoue Department of Gastrointestinal Oncology, Osaka International Cancer Institute
Author Yasushi Yamasaki Gastroenterology, Okayama University Hospital
Author Noriya Uedo Department of Gastrointestinal Oncology, Osaka International Cancer Institute
[ Summary ] Endoscopic treatment for superficial non-papillary duodenal tumor (SNADET) is associated with a high rate of adverse events because of the anatomical features (a narrow tortuous lumen and a thin wall) of the duodenum. Several endoscopic treatment methods such as endoscopic mucosal resection (EMR), endoscopic submucosal dissection, cold snare polypectomy, and laparoscopic endoscopic cooperative surgery, among others have been reported for the treatment of SNADETs. However, to date, a standard treatment method has not been established because each method is associated with specific merits and demerits. Our hospital policy involves choosing the treatment modality based on the size of lesions. We have observed that underwater EMR is useful for the treatment of SNADETs and shows a complete resection rate of 97 %, delayed bleeding rate of 0 % and intraprocedural and delayed perforation rate of 0 %.
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