Theme |
Progress in Endoscopic Ultrasonography for Biliopancreatic Diseases |
Title |
Diagnosis by EUS-FNA-Pancreas |
Author |
Hiromichi Iwaya |
Department of Gastroenterology, Aichi Cancer Center Hospital |
Author |
Susumu Hijioka |
Department of Gastroenterology, Aichi Cancer Center Hospital |
Author |
Nobumasa Mizuno |
Department of Gastroenterology, Aichi Cancer Center Hospital |
Author |
Takamichi Kuwahara |
Department of Gastroenterology, Aichi Cancer Center Hospital |
Author |
Nozomi Okuno |
Department of Gastroenterology, Aichi Cancer Center Hospital |
Author |
Kazuo Hara |
Department of Gastroenterology, Aichi Cancer Center Hospital |
[ Summary ] |
Endoscopic ultrasound‒guided fine needle aspiration (EUS‒FNA) is useful for diagnosing the main pancreatic disease, including conventional pancreatic cancer (PDAC), pancreatic neuroendocrine tumor (pNET), autoimmune pancreatitis (AIP), and pancreas cystic disease. Regarding PDAC, the diagnosis rate improves by combining a molecular biologic marker and genetic analysis, in addition to the improvement in the puncture needle. Additionally, EUS‒FNA plays a big role in diagnosis as well as qualitative diagnosis in pNET because the diagnosis is greatly associated with treatment strategy. In AIP, EUS‒FNA is an important tool to diagnose PDAC exclusively, but there is a lot of it when gathered tissue specimen quantity has a short problem only with an existing puncture needle and is careless for qualitative diagnosis. Whereas sensitivity is low and is not recommended, a cystic liquid analysis for viscous liquid property distinction and a differential diagnosis, either malignant or benign in pancreas cystic disease and cystic liquid cytodiagnosis in a utility under the present conditions because it is poor. |