Theme |
Endoscopic Treatment for Elderly Patients with Gastro‒intestinal Cancer |
Title |
Photodynamic Therapy for Early Esophageal Cancer |
Author |
Tatsunori Minamide |
Department of Gastroenterology and Endoscopy, National Cancer Center Hospital East |
Author |
Tomonori Yano |
Department of Gastroenterology and Endoscopy, National Cancer Center Hospital East |
[ Summary ] |
While definitive chemoradiotherapy (CRT) is the standard non‒surgical treatment for esophageal cancer in elderly patients, it is associated with a high rate of local failure. Although salvage surgery is generally indicated in such patients, it is associated with a high mortality and morbidity rate. We introduced photodynamic therapy (PDT) as a minimally invasive salvage treatment for local failure after CRT for esophageal cancer, with favorable results. PDT using talaporfin sodium, which was approved in 2015, is a minimally invasive and more convenient salvage treatment than PDT using porfimer sodium. |