臨牀消化器内科 Vol.32 No.4(3-4)


特集名 ESD手技の標準化に向けて
題名 安全なESのコツと偶発症の対処(4)十二指腸ESD
発刊年月 2017年 04月
著者 田島 知明 NTT東日本関東病院消化器内科
著者 大圃 研 NTT東日本関東病院消化器内科/NTT東日本関東病院内視鏡部
著者 里館 均 NTT東日本関東病院外科
著者 堀内 啓 NTT東日本関東病院病理診断科
著者 松橋 信行 NTT東日本関東病院消化器内科
【 要旨 】 表在性非乳頭部十二指腸腫瘍(superficial nonampullary duodenal tumor ; SNADT)に対するESDは技術的困難性や高率に発生する重篤な偶発症の問題もあり,他の消化管ESDとは一線を画する治療とされ,限られた先進的施設でのみ行われているのが現状である.しかし低侵襲治療という観点でESDは外科治療と比し患者のメリットは多大であることも事実である.今後,十二指腸ESDを安全かつ確実に行い標準化をはかるには,内視鏡医の技術向上とさまざまな手技の工夫,機器開発などが求められる.また,最近では腹腔鏡・内視鏡合同胃局所切除(laparoscopy endoscopy cooperative surgery ; LECS)を応用した手法も多く報告されており,治療を考えるうえでは外科医との十分な連携・バックアップ体制を整備しておくことも不可欠である.
Theme Towards Standardization of ESD Procedures
Title Know-how for the Practice of Endoscopic Submucosal Dissection for the Treatment of Superficial Nonampullary Duodenal Tumors and Strategies for Preventing Adverse Events
Author Tomoaki Tashima Department of Gastroenterology, NTT Medical Center Tokyo
Author Ken Ohata Department of Gastroenterology, NTT Medical Center Tokyo / Department of Endoscopy, NTT Medical Center Tokyo
Author Hitoshi Satodate 3Department of Surgery, NTT Medical Center Tokyo
Author Hajime Horiuchi 4Department of Pathology, NTT Medical Center Tokyo
Author Nobuyuki Matsuhashi Department of Gastroenterology, NTT Medical Center Tokyo
[ Summary ] Owing to the technical difficulty and high incidence of serious adverse events associated with the procedure, endoscopic submucosal dissection (ESD) for superficial nonampullary duodenal tumors (SNADT), it is recognized as a therapeutic procedure distinct from that for lesions in other segments of the gastrointestinal tract, and it is carried out only at advanced medical facilities. It is established beyond doubt, nevertheless, that ESD is more advantageous for patients compared to surgical treatment, being a minimally invasive treatment. Further improvement of the technical skills of the endoscopists, along with various procedural modifications and instrument developments are being sought in order to allow safe and secure practice of duodenal ESD and standardization of the procedure. Recently, there have been many reports of laparoscopic and endoscopic cooperative surgery (LECS) being applied. Close cooperation with surgeons and robust backup systems are also vital while considering treatment for SNADT.
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