臨牀消化器内科 Vol.30 No.4(2)


特集名 超高齢者の消化器疾患―その特徴と治療上の注意
題名 超高齢者に対する内視鏡検査上の注意点
発刊年月 2015年 04月
著者 荒川 廣志 東京慈恵会医科大学附属柏病院内視鏡部
著者 小山 誠太 東京慈恵会医科大学附属柏病院内視鏡部
著者 安達 世 東京慈恵会医科大学附属柏病院内視鏡部
著者 月永 真太郎 東京慈恵会医科大学附属柏病院内視鏡部
著者 梶原 幹生 東京慈恵会医科大学附属柏病院消化器・肝臓内科
著者 内山 幹 東京慈恵会医科大学附属柏病院消化器・肝臓内科
著者 小井戸 薫雄 東京慈恵会医科大学附属柏病院消化器・肝臓内科
著者 大草 敏史 東京慈恵会医科大学附属柏病院消化器・肝臓内科
著者 田尻 久雄 東京慈恵会医科大学消化器・肝臓内科/内視鏡科
著者 鈴木 博昭 東京慈恵会医科大学内視鏡科
【 要旨 】 超高齢者は主要臓器の機能や予備能が低下し複数の基礎疾患をもつ.内視鏡検査にとって高齢はリスクであり,大腸前処置や意識下鎮静法(CS)を行う場合も加齢のリスク評価と対策が必要である.大腸前処置は死亡例が報告されており,処置前に消化管閉塞の有無を必ず確認する.CSによる循環器系への抑制作用は比較的軽度だが,呼吸器系への抑制作用により上気道閉塞,低酸素血症,誤嚥,呼吸停止をきたす可能性があり,呼吸器系基礎疾患を有する場合は避けたほうがよい.鎮静薬投与時は健常成人より投与量を減量し,鎮静効果判定は投与3~5分後に行う.適切なモニタリングを行い,検査後60分程度リカバリーベッドで休息した後,家人が付き添い帰宅させるようにする.
Theme Digestive Diseases of the Aged Over 85 -- the Characteristics and Therapeutic Points
Title Conscious Sedation and Preparation for the Elderly in the Endoscopic Procedure
Author Hiroshi Arakawa Department of Endoscopy, The Jikei University Kashiwa Hospital
Author Seita Koyama Department of Endoscopy, The Jikei University Kashiwa Hospital
Author Sei Adachi Department of Endoscopy, The Jikei University Kashiwa Hospital
Author Shintaro Tsukinaga Department of Endoscopy, The Jikei University Kashiwa Hospital
Author Mikio Kajihara Division of Gastroenterology and hepatology, Department of Internal Medicine, The Jikei University Kashiwa Hospital
Author Kan Uchiyama Division of Gastroenterology and hepatology, Department of Internal Medicine, The Jikei University Kashiwa Hospital
Author Shigeo Koido Division of Gastroenterology and hepatology, Department of Internal Medicine, The Jikei University Kashiwa Hospital
Author Toshifumi Ohkusa Division of Gastroenterology and hepatology, Department of Internal Medicine, The Jikei University Kashiwa Hospital
Author Hisao Tajiri Division of Gastroenterology and Hepatology, Department of Internal Medicine and Endoscopy, The Jikei University School of Medicine
Author Hiroaki Suzuki Department of Endoscopy, The Jikei University School of Medicine
[ Summary ] Geriatric patients exhibit the organic dysfunction characteristics of aging, resulting in decreased functional reserve with which to respond to acute stress. Very elderly patients also frequently have complex underlying disease processes, which influence their stress response. Aging is a major risk factor in endoscopic procedures, and must be taken into consideration when evaluating risk of conscious sedation during endoscopy. Conscious sedation prevents exacerbation of hypertension and tachycardia caused by the stress response during endoscopy ; however, respiratory inhibition associated with conscious sedation may result in upper airway obstruction, hypoxia, aspiration, hypoventilation, or respiratory arrest. Therefore, the risks of conscious sedation should be weighed carefully in patients with pulmonary disease. Elderly patients should receive reduced doses of sedative agents compared to those administered to healthy adults, and be observed for a longer period for sedative effect (3 to 5 minutes). After endoscopy in the elderly, optimal monitoring includes a 60‒minute period of observation in a recovery bed and someone to accompany the patient at home after discharge to prevent falls.
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