| Theme |
Capsule Endoscopy -- Current States and the Latest Developments |
| Title |
Utility of Colon Capsule Endoscopy for Colorectal Neoplasia |
| Author |
Daisuke Ide |
Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University School of Medicine / Department of Endoscopy, The Jikei University School of Medicine |
| Author |
Shoichi Saito |
Department of Endoscopy, The Jikei University School of Medicine |
| Author |
Hiroko Inomata |
Department of Endoscopy, The Jikei University School of Medicine |
| Author |
Naoto Tamai |
Department of Endoscopy, The Jikei University School of Medicine |
| Author |
Hiroyuki Aihara |
Department of Endoscopy, The Jikei University School of Medicine |
| Author |
Masahiro Ikegami |
Department of Pathology, The Jikei University School of Medicine |
| [ Summary ] |
Colon capsule endoscopy (CCE) for colorectal examination can be availed under public insurance, based on a decision made by the Japanese ministry in April 2014. It is expected that CCE will be widely used in colorectal screening due to its lower degree of invasiveness. Moreover, the rat of colorectal cancer screening will also increase. The second generation of CCE, CCE-2, was released in the year 2009 in European countries. Recent overseas reports have documented the sensitivity of CCE-2 in detecting polyps with a diameter of > 6 mm as 84-91 %. Moreover, a prospective multicenter study in Japan, including our facility, found CCE-2, with a sensitivity of 94 %, to be a useful method in colorectal screening for Japanese patients. In our prospective study involving 48 patients, CCE-2 was found to have a sensitivity of 85.4 % in detecting colonic polyps. This study also found a low ratio of detection of rectal polyps (37.5 %, 3/8) due to the blowing out of booster, especially at the lower rectum. Caution should therefore be exercised in interpreting the findings with CCE-2 for rectal lesions. In the future, more trials for CCE-2 that aim at decreasing the booster are necessary to make it a useful modality for noninvasive screening of colon and rectum. |