臨牀消化器内科 Vol.30 No.12(3-5)


特集名 LECS(laparoscopy and endoscopy cooperative surgery)の新たな展開
題名 各種LECS手技 (5) NEWS
発刊年月 2015年 11月
著者 小田島 慎也 東京大学医学部附属病院消化器内科
著者 新美 惠子 東京大学医学部附属病院消化器内科/東京大学医学部附属病院検診部
著者 愛甲 丞 東京大学医学部附属病院胃食道外科
著者 山下 裕玄 東京大学医学部附属病院胃食道外科
著者 藤城 光弘 東京大学医学部附属病院消化器内科/東京大学医学部附属病院光学医療診療部
著者 瀬戸 泰之 東京大学医学部附属病院胃食道外科
著者 小池 和彦 東京大学医学部附属病院消化器内科
【 要旨 】 腹腔鏡・内視鏡合同手術(LECS)は,内視鏡的粘膜下層剝離術(ESD)の技術を用いた低侵襲な胃局所切除法である.しかし,LECSは管腔内外を交通させたうえで胃壁全層を切除する技術であるために,その適応はおもに粘膜下腫瘍に対する切除である.非穿孔式内視鏡的胃壁内反切除術(NEWS)は管腔を開放させることなく胃壁を全層切除することができる手技であり,腹腔内汚染や腫瘍の腹腔内播種の危険性を避けて腫瘍を切除することができるため,潰瘍を伴う粘膜下腫瘍や上皮性腫瘍に対する切除までをその適応に入れることができる.理論上リンパ節転移がない早期胃癌の治療としてESDが普及しているが,ESDによる処置が困難な病変などに対する手技としてもNEWSはその有効性が期待される.
Theme New Developments in Laparoscopy and Endoscopy Cooperative Surgery (LECS)
Title NEWS (non‒exposed endoscopic wall‒inversion surgery)
Author Shinya Kodashima Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo
Author Keiko Niimi Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo / Center for Epidemiology and Preventive Medicine, Graduate School of Medicine, The University of Tokyo
Author Susumu Aikou Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo
Author Hiroharu Yamashita Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo
Author Mitsuhiro Fujishiro Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo / Department of Endoscopy and Endoscopic Surgery, Graduate School of Medicine, The University of Tokyo
Author Yasuyuki Seto Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo
Author Kazuhiko Koike Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo
[ Summary ] Laparoscopy and endoscopy cooperative surgery (LECS) was invented as a minimally invasive full‒thickness resection technique mainly for gastric submucosal tumors. However, this method requires creating a hole in the gastric wall, which confers to patients the risk of intra-abdominal infection. The indication of LECS is limited to submucosal tumors only. Non‒exposed endoscopic wall‒inversion surgery (NEWS) was developed as an endoscopic full‒thickness resection technique without transluminal communication to prevent intra‒abdominal infection or tumor seeding. Therefore, NEWS may be useful to resect gastric submucosal tumors, not only those without ulceration but also those with ulceration, or node‒negative early gastric cancers. Although almost all node‒negative early gastric cancers (EGCs) could be resected by using endoscopic submucosal dissection, we sometimes experience EGCs that are difficult to resect endoscopically because of their location, shape, or submucosal fibrosis. Therefore, NEWS is thought to be effective for EGCs that are difficult to resect by using endoscopic submucosal dissection.
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