| Theme |
Cutting-edge Nutrition Therapy for Supporting the Treatment of Gastrointestinal Disorders |
| Title |
Nutritional Management and Prognosis for Gastrointestinal Malignancies |
| Author |
Takeshi Kubota |
Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine |
| Author |
Naoki Hiki |
Department of Gastroenterological Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research |
| Author |
Kazuma Okamoto |
Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine |
| Author |
Daisuke Ichikawa |
Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine |
| Author |
Shuhei Komatsu |
Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine |
| Author |
Eigo Otsuji |
Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine |
| [ Summary ] |
The importance of perioperative nutritional management for gastric cancer is outlined. This is based on our evidence gathered in research concerning the association between malnutrition and associated complications, as well as prognoses. Inflammation assessed by the Glasgow prognostic score (GPS) was adopted as a significant prognostic factor. Further, development of postoperative complications was also a prognostic factor. Co-morbidity was noted as a risk factor associated with complications. These results suggest the importance of preoperative management of nutrition in relation to co-morbidity. In addition, postoperative weight loss was reported to be a risk factor for continuation of S-1 adjuvant gastric cancer chemotherapy. For full cancer treatment, surgery and chemotherapy must be performed safely. Therefore we must closely observe our patientsʼ general condition, including their nutritional state. |