Theme |
Diagnosis and Treatment of Barrett's Esophagus : up-to-date |
Title |
Screening for Barrett's Esophagus by Ultrathin Transnasal Endoscope |
Author |
Takashi Kawai |
Endoscopy Center, Tokyo Medical University Hospital |
Author |
Kyosuke Yanagisawa |
Endoscopy Center, Tokyo Medical University Hospital |
Author |
Takemasa Sato |
Endoscopy Center, Tokyo Medical University Hospital |
Author |
Kenji Yagi |
Department of Gastroenterology, Tokyo Medical University Hospital |
Author |
Masakatsu Fukuzawa |
Endoscopy Center, Tokyo Medical University Hospital |
Author |
Chika Kusano |
Department of Gastroenterology, Tokyo Medical University Hospital |
Author |
Takuji Gotouda |
Department of Gastroenterology, Tokyo Medical University Hospital |
Author |
Fuminori Moriyasu |
Department of Gastroenterology, Tokyo Medical University Hospital |
[ Summary ] |
Background:A newly developed ultrathin transnasal endoscope, the GIF-XP290N (290N), makes possible a resolving power similar to the GIF-H260 at a distance of 3 mm. We conducted surveillance of subjects with Barrett's esophagus using a 290N. Palisade vessels and squamous epithelium islands may be clearly recognized with a 290N. Method & Results : Barrett's esophagus was confirmed in 50 out of 59 subjects (84.7%). Ultra close observation of Barrett's esophagus related mucosal structural patterns using narrow band imaging (NBI) revealed 8 cases with oval or round patterns, 17 with long straight patterns, 17 with villous patterns, 4 with cerebriform patterns, and 4 with irregular patterns according to the Goda classification. It is possible that observation of Barrett's esophagus related mucosal structural patterns is related to the presence of intestinal metaplasia, and may make possible early detection of Barrett's adenocarcinoma. |