臨牀消化器内科 Vol.28 No.5(2-5)


特集名 IBDと合併症
題名 腸管外合併症 (5) 凝固系異常
発刊年月 2013年 05月
著者 横山 薫 北里大学東病院消化器内科
【 要旨 】 炎症性腸疾患(IBD)の腸管外合併症の一つに血液の凝固能亢進による静脈血栓塞栓症(VTE)が挙げられ,代表的疾患は肺血栓塞栓症(PTE)と深部静脈血栓症(DVT)である.IBDにおけるVTE発現のリスクは高く,非IBDの1.5〜3.5倍,再発も2.5倍と高率である.またVTE入院例における死亡率も非IBDの2.1倍と高率であり,臨床医は常にVTEの合併に留意しながら診療を行う必要がある.
Theme Complication of Inflammatory Bowel Disease
Title Thrombosis and Inflammatory Bowel Disease
Author Kaoru Yokoyama Department of Gastroenterology, Kitasato University East Hospital
[ Summary ] Venous thromboembolism (VTE) caused by hypercoagulable states is an extraintestinal complication of inflammatory bowel disease (IBD). Representative conditions include pulmonary thromboembolism and deep vein thrombosis. Patients with IBD have a 1.5 to 3.5 times higher risk of VTE and a 2.5 times higher risk of recurrence than those with non-IBD. Patients with IBD who are hospitalized for VTE have a 2.1 times higher mortality rate than patients with non-IBD. Clinicians should always bear in mind the risk of VTE when conducting daily diagnosis and treatment.
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