| Theme |
Diagnostic and Interventional EUS -- Present Status and Future Perspectives |
| Title |
EUS-FNA for Pancreatobiliary and Mediastinal Lesions |
| Author |
Shomei Ryozawa |
Digestive Disease Center, Showa University Northern Yokohama Hospital (Department of Gastroenterology, Saitama Medical University International Medical Center) |
| Author |
Hirotoshi Iwano |
Digestive Disease Center, Showa University Northern Yokohama Hospital (Department of Gastroenterology, Saitama Medical University International Medical Center) |
| Author |
Kumiko Taba |
Digestive Disease Center, Showa University Northern Yokohama Hospital (Department of Gastroenterology, Saitama Medical University International Medical Center) |
| Author |
Shogo Ohkoshi |
Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author |
Haruhiro Inoue |
Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author |
Shin-ei Kudo |
Digestive Disease Center, Showa University Northern Yokohama Hospital |
| [ Summary ] |
Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) has been developed over the past 20 years. By using this technique, we are able to obtain cytologic and histologic material, which is difficult to obtain without laparotomies and is important for determining therapeutic strategies for lesions. Pancreatobiliary lesions and mediastinal lesions are major indications for EUS-FNA and high diagnostic values have been reported. Rapid on-site cytopathological evaluation (ROSE) provides highly reliable diagnoses. The diagnostic yield of EUS-FNA with ROSE in most studies exceeds 90 %. However, similarly favorable results without ROSE have been reported in selected studies. These results may not apply to all situations and should be interpreted in light of specific clinical situations and resource availability. Further controlled clinical studies may be needed to clarify the technical issues related to maximizing diagnostic yields from EUS-FNA. |