臨牀消化器内科 Vol.28 No.11(2)


特集名 下部直腸・肛門部疾患の診断と治療
題名 肛門管癌 ― とくに扁平上皮癌の早期診断と治療
発刊年月 2013年 10月
著者 岸原 輝仁 がん研有明病院消化器内科
著者 五十嵐 正広 がん研有明病院消化器内科
著者 森重 健二郎 がん研有明病院消化器内科
著者 千野 晶子 がん研有明病院消化器内科
著者 浦上 尚之 がん研有明病院消化器内科
著者 為我井 芳郎 がん研有明病院消化器内科
【 要旨 】 内視鏡による肛門管癌の診断と治療について述べた.
肛門管癌は,体表に近いにもかかわらず進行癌で発見されるものが多い.その理由は,痔核と誤診されたり,内視鏡観察においても安易に観察され見逃しの多いことなどが挙げられる.内視鏡診断は,肛門部を注意して観察することと反転観察により,早期診断が可能である.さらに,色素撒布と拡大観察を加え腫瘍ピットを観察することで腺癌の診断が可能となる.さらに,NBIを用いた拡大観察を行うことで扁平上皮癌の診断が可能である.それには食道のdysplasiaや癌でみられるものと同様の血管パターンを認識することにより早期発見や診断が可能である.
Theme Diagnosis and Treatment of Anorectal Disease
Title Diagnosis and Treatment of Anal Canal Cancer
Author Teruhito Kishihara Department of Gastroenterology, The Cancer Institute Hospital of JFCR
Author Masahiro Igarashi Department of Gastroenterology, The Cancer Institute Hospital of JFCR
Author Kenjiro Morishige Department of Gastroenterology, The Cancer Institute Hospital of JFCR
Author Akiko Chino Department of Gastroenterology, The Cancer Institute Hospital of JFCR
Author Naoyuki Uragami Department of Gastroenterology, The Cancer Institute Hospital of JFCR
Author Yoshiro Tamegai Department of Gastroenterology, The Cancer Institute Hospital of JFCR
[ Summary ] We describe endoscopic diagnosis and treatment of anal canal cancer. This type of cancer is often discovered only when in advanced stages, even though anal canal cancer occurs near the surface of the body. Major reasons for late diagnoses of anal canal cancer are considered to be misdiagnosis of conditions such as hemorrhoids. Early diagnosis of anal canal cancer through endoscopic diagnosis is possible by observing the anal region with care. However, reverse observation is important. During routine examinations, the anal canal is usually observed tangentially by conventional observation, making it impossible to observe the entire lesion in frontal views. Proper observation of the anal canal becomes possible when we reverse the scope axis. Furthermore, a diagnosis of adenocarcinoma is possible by magnifying the observation of a tumorʼs pit patterns with dye spraying. Furthermore, a diagnosis of squamous cell carcinoma is possible by performing a magnified observation using NBI systems. In other words, we may diagnose the presence of several types of anal canal cancer by observing blood vessel patterns, which are similar to those found in esophageal dysplasia or carcinoma.
戻る