| Theme |
Carcinogenesis Based on H. pylori-associated Gastritis -- Is Cancer Control Possible by the Eradication ? |
| Title |
Clinical Features of Gastric Cancer Detected after Helicobacter pylori Eradication and after Endoscopic Resection of Early Gastric Cancer |
| Author |
Yuichi Sato |
Department of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences |
| Author |
Masaaki Kobayashi |
Division of Endoscopy, Niigata University Medical and Dental Hospital |
| Author |
Manabu Takeuchi |
Department of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences |
| Author |
Satoru Hashimoto |
Division of Endoscopy, Niigata University Medical and Dental Hospital |
| Author |
Ken Nishikura |
Division of Molecular and Diagnostic Pathology, Niigata University Graduate School of Medical and Dental Sciences |
| Author |
Yutaka Aoyagi |
Department of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences |
| [ Summary ] |
Eradication of H. pylori is thought to prevent the development of gastric cancer. However, gastric cancer is sometimes discovered after successful eradication of H. pylori. We investigated the clinicopathological features of 29 lesions from metachronous gastric cancer detected after the successful eradication of H. pylori. of these lesions, nine were detected after endoscopic resection of early gastric cancer (gastric cancer; GC group), and 20 were detected in the group of patients without gastric cancer before eradication (non-GC group). There was no significant difference between the groups in terms of clinicopathological features, such as age, follow-up period, location in the stomach, macroscopic type, histological type, depth of invasion, and mucin phenotype of metachronous cancer. H. pylori eradication therapy does not prevent metachronous gastric cancer development. Therefore, it is important to perform surveillance endoscopy after eradication. |