臨牀消化器内科 Vol.27 No.13(5)


特集名 消化管リンパ腫―最近の知見
題名 消化管リンパ腫の内視鏡診断
発刊年月 2012年 12月
著者 大仁田 賢 長崎大学病院消化器内科
著者 磯本 一 長崎大学病院消化器内科
著者 松島 加代子 長崎大学病院消化器内科
著者 林 徳眞吉 長崎大学病院病理部
著者 宿輪 三郎 三佼会宮崎病院
著者 中尾 一彦 長崎大学病院消化器内科
【 要旨 】 消化管悪性リンパ腫の内視鏡像は多彩であり,胃では表層型・潰瘍型・隆起型・決潰型・巨大皺襞型に,小腸では限局型(隆起型,潰瘍型,その他),びまん浸潤型に,大腸では限局型(腫瘤型,潰瘍型,限局浸潤型)とびまん型に分類される.胃悪性リンパ腫のNBI拡大所見は表層型においては,腺管の大小不同,膨化・大型化,破壊像,不規則な分布やリンパ濾胞の存在,背景と同様の粘膜の介在などである.また,蛇行,分岐した樹枝状の血管がリンパ濾胞を思わせる白色調領域に一致して認められるのも特徴である.癌との鑑別はおもに粘膜下層を主体としており潰瘍辺縁に上皮性の変化を認めないことである.
Theme Gastrointestinal Lymphoma -- Recent Advances in the Diagnosis and Management
Title Endoscopic Diagnosis of Gastrointestinal Malignant Lymphomas
Author Ken Ohnita Department of Gastroenterology and Hepatology, Nagasaki University Hospital
Author Hajime Isomoto Department of Gastroenterology and Hepatology, Nagasaki University Hospital
Author Kayoko Matsushima Department of Gastroenterology and Hepatology, Nagasaki University Hospital
Author Tomayoshi Hayashi Department of Pathology, Nagasaki University Hospital
Author Saburo Shikuwa Sankoukai Miyazaki Hospital
Author Kazuhiko Nakao Department of Gastroenterology and Hepatology, Nagasaki University Hospital
[ Summary ] There are various endoscopic findings for gastrointestinal malignant lymphoma. Malignant lymphoma of the stomach is endoscopically divided into the superficial type, ulcerated type, tumorous type, collapsed type and giant fold type. Malignant lymphoma of the small intestine is endoscopically divided into the localized type and the diffusely infiltrated type. Malignant lymphoma of the large intestine is endoscopically divided into the localized type and diffuse type. Findings of gastric lymphoma with magnifying endoscopy using narrow band imaging include diversity in pit size, ballooning of gastric pits, increased pit size, destruction of pits and irregular distribution of pits, the existence of lymphoid follicles, and intercalation of pits, resembling the background mucosa. In addition, tree like microvessels are recognized in accordance with whitish lesions, Which are regarded as lymphoid follicles. Discrimination from cancer is made through the following ; the existence of lymphoma mainly in the submucosa, and the absence of epithelial changes at ulcer margins in cases of lymphoma.
戻る