臨牀消化器内科 Vol.27 No.10(1-3)


特集名 内視鏡検査・治療時の管理は?
題名 上部消化管内視鏡 (3) 食道のEMR・ESD時の患者管理
発刊年月 2012年 09月
著者 若槻 俊之 佐久総合病院胃腸科
著者 小山 恒男 佐久総合病院胃腸科
著者 宮田 佳典 佐久総合病院胃腸科
著者 友利 彰寿 佐久総合病院胃腸科
著者 高橋 亜紀子 佐久総合病院胃腸科
著者 篠原 知明 佐久総合病院胃腸科
【 要旨 】 食道癌には高リスク患者が多く,安全なESDにはさまざまな準備や工夫が必要である.術前には抗凝固薬,抗血小板薬の確認,休薬が重要で,術中は血圧,脈拍,SpO2を計測・記録し,抑制,血栓予防,誤嚥防止などの工夫が必要である.麻酔時には使用する鎮静薬,鎮痛薬の特性理解が大切で,アルコール多飲者ではベンゾジアゼピン系薬剤との交差耐性のため同薬剤が効きにくい.したがって,胃ESDよりも麻酔が難しく,多剤併用が必要となる場合が多い.偶発症時には全身状態を把握し,安全性確保を最優先すべきである.術後は気腫,吐下血,胸痛,発熱の有無に注意して患者を観察する.食道ESDでの後出血はまれであり,抗凝固薬,抗血小板薬は術後早期に再開する.
Theme Patient Management During Endoscopic Examination and Treatment
Title Patient Care for Esophageal Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection
Author Toshiyuki Wakatsuki Department of Gastroenterology, Saku Central Hospital
Author Tsuneo Oyama Department of Gastroenterology, Saku Central Hospital
Author Yoshinori Miyata Department of Gastroenterology, Saku Central Hospital
Author Akihisa Tomori Department of Gastroenterology, Saku Central Hospital
Author Akiko Takahashi Department of Gastroenterology, Saku Central Hospital
Author Tomoaki Shinohara Department of Gastroenterology, Saku Central Hospital
[ Summary ] Esophageal cancer patients have many risks including liver dysfunction, emphysema, and cardiovascular diseases. Therefore, various plans are required in order to perform safer ESD procedures. Warfarin and antiplatelet drugs should be withdrawn a few days before ESD to decrease the risk of hemorrhage. Blood pressure, heart rate and oxygen saturation should be checked and recorded during ESD. An automatic leg massager is useful to prevent deep venous thrombosis. Insertion of an over tube is useful to prevent aspirational pneumonia.
Benzodiazepines with intravenous narcotics are commonly used for sedation. However, control of sedation is sometimes difficult, because alcoholics often have a resistance to benzodiazepines. Therefore, sedation for esophageal ESD is more difficult than that for gastric ESD. Sometimes sedation with multiple medications is necessary for esophageal ESD. Overall conditions should be observed when complications such as perforation have occurred. Vital signs, hematemesis, melena, chest pain, emphysema and body temperature should be scrutinized after ESD. Warfarin and antiplatelet drugs should be restarted soon after ESD to prevent cardiovascular disease because the risk of delayed bleeding after esophageal ESD is rare.
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