臨牀消化器内科 Vol.26 No.9(5)


特集名 腹部超音波検査 up-to-date
題名 肝細胞癌に対する造影超音波検査とDynamic CT,MRIとの比較
発刊年月 2011年 08月
著者 井上 達夫 近畿大学医学部消化器内科
著者 工藤 正俊 近畿大学医学部消化器内科
【 要旨 】 本稿では造影超音波検査の肝細胞癌の診断能をdynamic CT,Gd-EOB-MRI と比較検討を行った.対象は2008年2月〜2010年4月に当院でGd-EOB-MRIを施行し,造影超音波検査,dynamic CTのいずれかを施行した323症例,482結節.平均年齢は68.3歳,平均腫瘍径は13.8±8.4 mm.多血性肝細胞癌の各検査における検出能に統計学的な有意差を認めなかったが,Gd-EOB-MRI の検出能が最も優れていた.乏血性結節のGd-EOB-MRI の肝細胞相とpost-vascular phaseの比較検討では,post-vascular phaseでdefectを示さない結節,すなわち網内系機能の保持された例においても大多数の症例でGd-EOBMRIの肝細胞相ではlow intensityを示し,乏血性の境界病変の検出においてGd-EOB-MRIは非常に有用であると考えられる.
Theme Abdominal Ultrasonography up-to-date
Title Contrast-enhanced Ultrasonography for Hepatocelullar Carcinoma ; Comparing Multidetector Row CT to Dynamic Magnetic Resonance Imaging
Author Tatsuo Inoue Department of Gastroenterology and Hepatology, Kinki University School of Medicine
Author Masatoshi Kudo Department of Gastroenterology and Hepatology, Kinki University School of Medicine
[ Summary ] We evaluated the diagnostic potential of contrast-enhanced ultrasonography (US) to reveal hepatocellular carcinomas (HCC). We also compared US to mutidetector row (MD) CT and, images produced with infusions of gadoxetic acid [gadolinium-ethoxybenzyl (Gd-EOB) or images obtained by employing diethylenetriaminopentoacetic acid (DTPA)] for MRI. The sensitivity of contrast-enhanced US, MDCT and Gd-EOB-DTPA MRI were not significantly deferent, although Gd-EOB-DTPA, MRI exhibited the best results.
In regard to borderline lesions, hepatobiliary phase Gd-EOB-DTPA MRI image videntified most lesions as low intensity areas, while post-vascular phase images obtained with contrast-enhanced US failed to detect them. Due to these observations, hepatobiliary phase Gd-EOB-DTPA MRI images are useful in early detection of borderline lesions. Further study is needed to ascertain more accurate diagnostic techniques to diagnose HCCs and borderline lesions.
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