Theme |
Various Subjects of Long-term Following Patients with Ulcerative Colitis |
Title |
Influence of Pregnancy on Course of Ulcerative Colitis |
Author |
Reiko Kunisaki |
Inflammatory Bowel Disease Center, Yokohama City University Medical Center |
Author |
Hisae Yamamoto |
Inflammatory Bowel Disease Center, Yokohama City University Medical Center |
Author |
Hideaki Kimura |
Inflammatory Bowel Disease Center, Yokohama City University Medical Center |
Author |
Shin Maeda |
Department of Gastroenterology, Yokohama City University Graduate School of Medicine |
Author |
Mizuho Yamaguchi |
Perinatal Center for Maternity and Neonate, Yokohama City University Medical Center |
Author |
Mika Okuda |
Perinatal Center for Maternity and Neonate, Yokohama City University Medical Center |
Author |
Tsuneo Takahashi |
Perinatal Center for Maternity and Neonate, Yokohama City University Medical Center |
[ Summary ] |
At the time of conception, the risk of disease relapse from a quiescent state is the same as it is for non-pregnant ulcerative colitis patients. If conception occurs at a time when the disease is active, two thirds of the patients will experience persistent symptoms and of these, two thirds will deteriorate. It seems that pregnancy influences the overall course of UC positively, because clinical activity declines with pregnancy. Mothers with UC seem to have lower relapse rates in the years after pregnancy. |