臨牀消化器内科 Vol.26 No.8(4)


特集名 潰瘍性大腸炎―長期経過観察例の諸問題
題名 高齢発症例の推移
発刊年月 2011年 07月
著者 髙橋 晴彦 福岡大学筑紫病院消化器内科
著者 久部 高司 福岡大学筑紫病院消化器内科
著者 松井 敏幸 福岡大学筑紫病院消化器内科
【 要旨 】 高齢化社会,高齢発症の増加,長期観察例の増加に伴い,潰瘍性大腸炎(UC)患者の高齢化が進行している.高齢発症患者の増加に伴い,UCの発症年齢分布では15〜29歳と55〜64歳の二峰性を示す傾向がある.高齢発症UCの臨床経過や予後に関してはさまざまであり定見がない.しかし,高齢者では他疾患の合併が多く,薬物治療による副作用の発現頻度も高いため,高齢者UC患者の治療には内科と外科が連携をとり,内科的治療困難な場合には早期の手術を含めた治療方針の選択が必要である.今後増加の一途をたどると予想される高齢者UC に対してはその特徴を知り,より緻密な治療戦略を立てることが必要である.
Theme Various Subjects of Long-term Following Patients with Ulcerative Colitis
Title Changes in Incidence of Elderly Onset Ulcerative Colitis
Author Haruhiko Takahashi Department of Gastroenterology, Fukuoka University Chikushi Hospital
Author Takashi Hisabe Department of Gastroenterology, Fukuoka University Chikushi Hospital
Author Toshiyuki Matsui Department of Gastroenterology, Fukuoka University Chikushi Hospital
[ Summary ] Changes in the average age of ulcerative colitis (UC) patients have progressed in association with the aging of the population, increases in elderly onset, and increases in longterm follow-up cases. The increase in cases of onset in the elderly has been accompanied by a tendency for the age distribution of UC to exhibit two peaks, one in the 15- to 29-year-old group and in the 55- to 64-year-old group. Clinical courses and outcomes for UC patients with elderly onset vary, and there is no consensus as to why this is so. However, because the elderly often have other diseases and also experience a high incidence of adverse effects, internists and surgeons must collaborate in the treatment of elderly UC patients. It is necessary to select a treatment plan which includes early surgery when medical treatment is difficult. There is an increased need to learn the characteristics of UC in the elderly, because of expected steady increases in future numbers. It is also necessary to establish more sophisticated treatment strategies.
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