臨牀消化器内科 Vol.26 No.1(7)


特集名 膵癌up-to-date
題名 EUS
発刊年月 2011年 01月
著者 小牧 孝充 近畿大学医学部内科消化器内科
著者 北野 雅之 近畿大学医学部内科消化器内科
著者 坂本 洋城 近畿大学医学部内科消化器内科
著者 今井 元 近畿大学医学部内科消化器内科
著者 鎌田 研 近畿大学医学部内科消化器内科
著者 宮田 剛 近畿大学医学部内科消化器内科
著者 工藤 正俊 近畿大学医学部内科消化器内科
【 要旨 】 膵腫瘍におけるEUS-FNA(endoscopic ultrasound guided fine needle aspiration)の目的は,良・悪性の鑑別診断,組織型診断,病期診断である.膵疾患に対する検体採取率は92~100%で,感度85%,特異度98%,正診率88%,偶発症0.5~2.5%と報告されている.ExPHD モードを使用した造影EUS 検査では腫瘍内の実質染影像を評価することで,Ⅰ型:avascular pattern(脂肪壊死など),Ⅱ型:hypovascular pattern(通常型膵癌など),Ⅲ型:isovascular pattern(腫瘤形成性膵炎など),Ⅳ型:hypervascular pattern(内分泌腫瘍など)の四つのパターンに分けられる.
Theme Pancreatic Cancer : Up-to-date
Title EUS for Diagnosis of Pancreatic Disease
Author Takamitsu Komaki Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kinki University School of Medicine
Author Masayuki Kitano Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kinki University School of Medicine
Author Hiroki Sakamoto Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kinki University School of Medicine
Author Hajime Imai Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kinki University School of Medicine
Author Ken Kamata Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kinki University School of Medicine
Author Tsuyoshi Miyata Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kinki University School of Medicine
Author Masatoshi Kudo Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kinki University School of Medicine
[ Summary ] The indications for endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) for pancreatic lesions are as follows:differential diagnosis of benign and malignant lesions and characterization of neoplasms and cancer staging. The sensitivity, specificity and accuracy of EUSFNA for diagnosing pancreatic cancer are reportedly 80-90%, 100%, and 85-95%, respecitvely. The overall complication rate appears to be 0.5-2.5%.
Recently, second generation contrast agents for ultrasonography have been developed and contrast-enhanced harmonic imaging with EUS (CH-EUS) is now available. In a contrast-enhanced harmonic EUS study, using the ExPHD mode, pancreatic tumors were classified into four vascular patterns (avascular, hypovascular, isovascular and hypervascular).
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