臨牀消化器内科 Vol.26 No.1(10)


特集名 膵癌up-to-date
題名 手術療法
発刊年月 2011年 01月
著者 菱田 光洋 名古屋大学大学院医学系研究科消化器外科学
著者 藤井 努 名古屋大学大学院医学系研究科消化器外科学
著者 中尾 昭公 名古屋大学大学院医学系研究科消化器外科学
【 要旨 】 通常型膵癌はきわめて難治であり,外科切除が長期生存を期待するための必要条件である.近年では,画像診断が進歩し,比較的有効な化学療法が開発されてきた.現在の膵癌治療は,過不足のないリンパ節郭清,神経叢郭清,門脈合併切除などを行い,癌遺残のない確実な切除を安全に施行し,速やかに補助化学療法を開始することが重要とされている.本稿では,当教室における通常型膵癌に対する手術適応や術式について概説する.
Theme Pancreatic Cancer : Up-to-date
Title Surgical Criteria and Techniques for Pancreatic Cancer Treatment
Author Mitsuhiro Hishida Department of Surgery II (Gastroenterological Surgery), Nagoya University Graduate School of Medicine
Author Tsutomu Fujii Department of Surgery II (Gastroenterological Surgery), Nagoya University Graduate School of Medicine
Author Akimasa Nakao Department of Surgery II (Gastroenterological Surgery), Nagoya University Graduate School of Medicine
[ Summary ] Pancreatic cancer has the worst prognosis of all gastrointestinal neoplasms. Only surgical resection offers a possibility of cure. Aggressive resection is indicated if surgically cancer-negative margins are possible. Carcinoma invasion of the portal vein system is common in pancreatic cancer. Survival rates for patients who undergo portal vein resection are much higher than those which are unresectable. We have performed pancreatoduodenectomies with portal vein resection using catheter-bypass and non-touch isolation techniques. These techniques contribute to the safety of our operative procedures. Recently, the combination of surgery and chemotherapy has improved the prognoses for these patients. It is important to start adjuvant chemotherapy as soon as possible after pancreatic cancer resection.
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