臨牀消化器内科 Vol.25 No.9(6)


特集名 自己免疫性膵炎
題名 画像診断
発刊年月 2010年 08月
著者 入江 裕之 佐賀大学医学部放射線科
著者 蒲地 紀之 佐賀大学医学部放射線科
著者 野尻 淳一 佐賀大学医学部放射線科
著者 江頭 秀哲 佐賀大学医学部放射線科
著者 笹栗 弘平 佐賀大学医学部放射線科
著者 工藤 祥 佐賀大学医学部放射線科
【 要旨 】 自己免疫性膵炎(AIP)のUS,CT,MRI所見について解説した.膵腫大の程度が軽微な場合には他の特徴的な画像所見を理解しておくことが重要となる.USでは”ソーセージ様”と呼ばれる低エコーのびまん性腫大が特徴である.CTではダイナミックCTでの遅延性増強パターンが特徴であるが,病態に応じて多彩な所見を呈する可能性があることも認識すべきである.MRIではT1強調像での低信号,ダイナミックMRIでの遅延性増強パターンが特徴である.病変周囲を取り囲むcapsule-like rimは病変辺縁部の強い線維化を反映しており,特異度は高い.限局性のAIPと膵癌の鑑別は画像所見のみでは困難なことが少なくなく,総合的に診断することが必要である.
Theme Autoimmune Pancreatitis
Title US, CT and MRI Findings of Autoimmune Pancreatitis
Author Hiroyuki Irie Department of Radiology, Faculty of Medicine, Saga University
Author Noriyuki Kamochi Department of Radiology, Faculty of Medicine, Saga University
Author Junichi Nojiri Department of Radiology, Faculty of Medicine, Saga University
Author Yoshiaki Egashira Department of Radiology, Faculty of Medicine, Saga University
Author Kouhei Sasaguri Department of Radiology, Faculty of Medicine, Saga University
Author Sho Kudo Department of Radiology, Faculty of Medicine, Saga University
[ Summary ] US, CT and MRI findings of autoimmune pancreatitis (AIP) are commented on based on the study titled, "Clinical diagnostic criteria of autoimmune pancreatitis 2006". Evaluation of pancreatic enlargement either diffuse or localized, is the essential evaluating point for imaging studies. However, other characteristic imaging findings are also required in order to obtain correct diagnoses. With US, hypoechoic pancreatic enlargement is observed to be characteristic of AIP, including a "sausage-like appearance". Dynamic studies, either with CTs, MRIs, or AIP usually exhibit delayed enhancement patterns. The signal intensity of T1-weighted MRIs is usually diminished, however, it varies in T2-weighted images. Attention should be paid to the fact that there are various imaging findings from AIP, probably due to various disease conditions. At present, MRCP cannot be used in evaluating main pancreatic duct narrowing, however, it may be used in the near feature with improvements in image quality. Differentiation between focal type AIP and pancreatic cancer is often difficult, although there are several differentiating points, such as the contours of the affected portion which is usually smooth. In addition, AIP does not obliterate peri-pancreatic fat tissue in contrast to pancreatic cancer.
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