| [ Summary ] |
Ethnic factors are defined as those factors relating to the genetic and physiologic (intrinsic) as well as cultural and environmental (extrinsic) characteristics of a population. It is important to consider intrinsic factors such as the morphorism of CYP2C19 or weight, and extrinsic factors such as H. pylori, endoscopic skill level, food, medical insurance systems, or NSAID dosage. This must be done in differences between order to extrapolate foreign clinical data concerning peptic ulcers to those in Japan. Various ethnic factors influence diagnosis, therapies, and means of prevention. It is difficult to extrapolate all the data without modifying our analysis. If we interpret the differences concerning ethnic factors well enough, Western data may be helpful in developing means of clinical peptic ulcer management. Well-controlled and well-designed clinical research will be necessary in Japan. |