| Theme |
Intraductal Papillary Mucinous Neoplasm (IPMN) |
| Title |
Chronological Changes in Disease Concepts Concerning Intraductal Papillary Mucinous Neoplasms and Mucinous Cystic Neoplasms |
| Author |
Satoshi Sugimori |
Department of Gastroenterology, Aichi Cancer Center Hospital |
| Author |
Kenji Yamao |
Department of Gastroenterology, Aichi Cancer Center Hospital |
| Author |
Kazuo Hara |
Department of Gastroenterology, Aichi Cancer Center Hospital |
| Author |
Tadayuki Takagi |
Department of Gastroenterology, Aichi Cancer Center Hospital |
| Author |
Nobumasa Mizuno |
Department of Gastroenterology, Aichi Cancer Center Hospital |
| Author |
Akira Sawaki |
Department of Gastroenterology, Aichi Cancer Center Hospital |
| [ Summary ] |
The term MCN was proposed by Compagno in 1978. The term IPMN is based on information related to mucinproducing pancreatic cancer which Ohashi and Takagi proposed in the early 1980's. Later, many researchers examined the lesions in detail clinicopathologically, and noticed that they include adenomas and types of hyperplasia,in addition to carcinoma. They re-named these lesions "mucin-producing cystic tumors of the pancreas" and a variety of other names. Since these terms were first proposed about 30 years ago, concepts concerning these terms have remained unclear. Japan had an important role in developing these concepts, including the WHO classification developed in 1996 and the AFIP classification made in 1997 to clarify these definitions. IPMN and MCN have many unknown qualities. It is necessary to accumulate information and analyze it for improved patient care. |