Theme |
Intestinal Mucosal Damage Induced by Drugs |
Title |
Colonic Mucosal Lesions Associated with Low Dose Aspirin |
Author |
Tomoyoshi Shibuya |
Department of Gastroenterology, Juntendo University School of Medicine |
Author |
Toshifumi Ohkusa |
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kashiwa Hospital, The Jikei University School of Medicine |
Author |
Sumio Watanabe |
Department of Gastroenterology, Juntendo University School of Medicine |
[ Summary ] |
NSAID users have a significantly higher incidence of colonic lesions than non-NSAIDs-users.Low dose aspirin (LDA) is widely used because it reduces the risk of vascular events in patients with coronary and cerebrovascular disease.There has been a substantial increase in prescriptions for LDA in recent years.LDA users have a significantly higher incidence of colonic lesions than non LDA-users.It is necessary to be aware of not only gastroduodenal ulcers but also colonic lesions with long-term use of LDA. |