臨牀消化器内科 Vol.24 No.10(7)


特集名 色素内視鏡を見直す -- 画像強調観察法との比較
題名 胃上皮性腫瘍の腺管構造と血管網の検討 -- クリスタルバイオレット染色とNBI同時観察の有用性
発刊年月 2009年 09月
著者 大仁田 賢 長崎大学病院消化器内科
著者 磯本 一 長崎大学病院消化器内科
著者 宿輪 三郎 三佼会宮崎病院
【 要旨 】 クリスタルバイオレット(CV)染色により胃上皮性腫瘍の腺管構造を観察し,さらに CV染色下で Narrow Band Imaging(NBI)観察を施行し,腺管構造と血管網を対比し検討した.腺管構造に関しては,胃腺腫ではおもに均一の pitを認めたが,癌になると pitの大小不同,構造の不整,小型化,無構造を認める頻度が高くなり,そのなかでも高分化腺癌では pitの大小不同,構造の不整を認め,中分化腺癌では小型化を,低分化腺癌,印環細胞癌では無構造を多く認めた.血管網では分化型癌では網目状血管,ループ状血管を,未分化型癌では縮緬状血管を多く認めた.腺管構造と血管網の対比においては,pit が崩れた部位に血管増生や血管網の消失を認めた.
Theme Re-thinking Chromoendoscopy
Title Gastric Epithelial Neoplasms -- Magnified Endoscopic Findings -- Magnifying Chromoendoscopywith Crystal Violet and Crystal Violet PlusNarrow Band Imaging
Author Ken Ohnita Department of Gastroenterology, Nagasaki University Hospital
Author Hajime Isomoto Department of Gastroenterology, Nagasaki University Hospital
Author Saburo Shikuwa Sankokai Miyazaki Hospital
[ Summary ] We report on magnified endoscopic findings related to early gastric cancer and gastric adenoma. Magnifying chromoendoscopy with crystal violet and crystal violet staining plus Narrow Band Imaging (NBI) was performed to diagnose early gastric cancer and gastric adenoma. Long tubular pit patterns indicated adenomas. Well differentiated adenocarcinoma and papillary adenocarcinoma often exhibited different sized pit or destructive pit patterns. Small round pit patterns were most commonly found in moderately differentiated adenocarcinoma. The non-structured patterns suggested undifferentiated adenocarcinoma (poorly differentiated adenocarcinoma and signet ring cell carcinoma). In microvessels, fine network patterns and loop patterns were seen in defferentiated adenocarcinoma. Corkscrew patterns were observed in undifferented adenocarcinoma. In contrast to superficial structures and microvessels, increases in or dissipation of blood vessels areconsidered to be non-structurally related.
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