| Theme |
Consensus Terminology in Endoscopic Imaging -- Focusing on Image-enhanced Endoscopy |
| Title |
Autofluorescence Endoscopy for Detection and Differential Diagnosis of Gastrointestinal Neoplastic Lesions |
| Author |
Hiroyuki Aihara |
Department of Endoscopy, The Jikei University School of Medicine |
| Author |
Shoichi Saitoh |
Department of Endoscopy, The Jikei University School of Medicine |
| Author |
Hisao Tajiri |
Department of Endoscopy, The Jikei University School of Medicine / Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University School of Medicine |
| [ Summary ] |
The Autofluorescence Imaging System (AFI system, Olympus Medical Systems, Tokyo, Japan) is a novel videoendoscope system developed to detect the faint autofluorescence from the gastrointestinal wall. The main fluorophore responsible for gastrointestinal autofluorescence is considered to be collagen in the submucosal layer. That layer emits less autofluorescence where there are neoplastic lesions, due to their pathological characteristics. The AFI system produces images of neoplastic lesions in magenta tones and non-neoplastic lesions or normal mucosa in green tones based on the balance of autofluorescence intensity and reflected green light intensity. Optical biopsies, using autofluorescence endoscopy (AFE) may be possible by establishing diagnostic criteria for endoscopic observations using the AFI system, which does not require magnified observation or dye spraying. |