臨牀消化器内科 Vol.23 No.11(3)


特集名 大腸pit pattern
題名 pit patternによる腫瘍・非腫瘍の鑑別 -- 色素使用による拡大内視鏡の手技とコツを含めて
発刊年月 2008年 10月
著者 桐山 真典 国立がんセンター中央病院内視鏡部
著者 松田 尚久 国立がんセンター中央病院内視鏡部
著者 中島 健 国立がんセンター中央病院内視鏡部
著者 斎藤 豊 国立がんセンター中央病院内視鏡部
【 要旨 】 色素使用下大腸拡大内視鏡診断・pit pattern診断により,病変発見後,瞬時に腫瘍・非腫瘍の鑑別を行い,適切な治療方針の決定が可能となる.手技の基本として良好な観察条件を得ること (前処置,蠕動抑制,吸引,洗浄) が重要である.インジゴカルミンは,病変の発見,質的・量的診断,範囲診断など多くの場面で使用される.クリスタルバイオレットは,通常観察で早期癌を疑った病変に対し,内視鏡治療・外科的手術の選択決定の深達度診断として用いる.大腸病変の質的診断 (腫瘍・非腫瘍の鑑別) のためのpit pattern診断および病変の拡大観察手技は,比較的その習得が容易であり,日常診療においてきわめて重要な手技である.
Theme Pit Pattern Classification in colorectal Lesion
Title Differential Diagnosis between Neoplastic and Non-neoplastic Lesions Using Magnifying Colonoscopy and Chromoendoscopy
Author Shinsuke Kiriyama Department of Endoscopy, National Cancer Center Hospital
Author Takahisa Matsuda Department of Endoscopy, National Cancer Center Hospital
Author Takeshi Nakajima Department of Endoscopy, National Cancer Center Hospital
Author Yutaka Saito Department of Endoscopy, National Cancer Center Hospital
[ Summary ] The combination of magnifying colonoscopy and chromoendoscopy using indigo carmine and crystal violet is feasible technique for differential diagnosis between non-neoplastic and neoplastic lesions. Furthermore, it is possible to decide on a therapeutic strategy for treatment of lesions, such as surgery, endoscopic treatment or observation. Maintaining the condition of colonoscopy is important for the use of magnifying chromoendoscopy, through such techniques as preparation, avoiding peristalsis, suctioning and washing. Magnification using indigo carmine dye spraying is useful for detection and differential diagnosis of malignant or benign tumors. Magnifying chromoendoscopy using crystal violet is performed for more accurate diagnosis regarding colorectal lesions at earlier stages. Pit pattern diagnosis and magnifying endoscopic techniques for differential diagnosis to separate non-neoplastic from neoplastic lesions of the colon and rectum are comparatively easy to master. The combination of magnifying colonoscopy and chromoendoscopy is the most reliable method for routine endoscopic diagnosis of the colon and rectum.
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