臨牀消化器内科 Vol.22 No.5(3)


特集名 門脈圧亢進症の診断と治療
題名 EUSからみた食道静脈瘤の診断と治療
発刊年月 2007年 05月
著者 中村 真一 東京女子医科大学消化器病センター
著者 村田 洋子 現 ムラタムリニック
著者 今井 隆二郎 東京女子医科大学消化器病センター
著者 岸野 真衣子 東京女子医科大学消化器病センター
著者 小西 洋之 東京女子医科大学消化器病センター
著者 白鳥 敬子 東京女子医科大学消化器病センター
【 要旨 】 超音波内視鏡検査 (endoscopic ultrasonography ; EUS) は胃噴門部周囲の血管群,貫通血管,傍食道静脈,穿通枝などの食道胃壁外の血管と食道静脈瘤の関係を観察するのに適した検査法である.EUSによる血行動態の検討から,左胃静脈前枝系がおもな供血路で,静脈瘤に並列するほかの側副血行路を有さない症例では,内視鏡的硬化療法 (endoscopic injection sclerotherapy ; EIS) に比し内視鏡的静脈瘤結紮術 (endoscopic variceal ligation ; EVL) の再発率が有意に高く,一方,傍食道静脈を有し,穿通枝が供血路となる症例では,EISとEVLの治療成績は同等であることが判明した.EUS所見からEISとEVLの選択,粘膜線維化治療の要否,再発の予知に関する多くの情報が得られ,EUSは合理的で安全な食道静脈瘤治療を行うために不可欠な検査である.
Theme Diagnosis and Treatment of Portal Hypertention
Title Usefulness of Endoscopic Ultrasonography for Diagnosis and Treatment of Esophageal Varices
Author Shinichi Nakamura Institute of Gastroenterology, Tokyo Women's Medical University
Author Yoko Murata Murata Clinic
Author Ryujiro Imai Institute of Gastroenterology, Tokyo Women's Medical University
Author Maiko Kishino Institute of Gastroenterology, Tokyo Women's Medical University
Author Hiroyuki Konishi Institute of Gastroenterology, Tokyo Women's Medical University
Author Keiko Shiratori Institute of Gastroenterology, Tokyo Women's Medical University
[ Summary ] At the present time, both endoscopic injection sclerotherapy (EIS) and endoscopic variceal ligation (EVL) are widely performed as endoscopic treatments for esophageal varices. It is necessary for safe and rational treatment to understand variceal hemodynamics before treatment. It is impossible to clearly visualize the relationship between regional vascular systems inside and outside the esophageal wall from the cardia of the stomach to the distal esophagus with conventional endoscopy. In this respect, endoscopic ultrasonography (EUS) is a useful method for performing evaluation, both before and after treatment since, it is capable of clearly depicting the relationship between esophageal varices and vascular systems outside the esophageal wall and is noninvasive. We observed vascular patterns of esophageal varices using 3 D-EUS. The results obtained with EVL and EIS were similar in patients with paraesophageal veins arising from the posterior branch of the left gastric vein (LGV) with perforating veins as the feeding vessels. However in patients without paraesophageal veins whose feeding vessels were mainly the anterior branches of the LGV, EVL was associated with a higher recurrence than EIS and thus the feeding vessels should be obliterated by intravariceal EIS. The vascular pattern of esophageal varices classified by 3 D-EUS enabled us to clarify the criteria for making a choice of endoscopic procedures.
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