| Theme |
Guidebook of Pathology for Gastroenterologists and Hepatologists ; Including Special Stains and Immunohistochemistry |
| Title |
Pathological Diagnosis of Malignant Lymphoma of the Digestive Organ |
| Author |
Hideko Yamamoto |
Department of Pathology and Clinical Laboratories, Nagoya University Hospital |
| Author |
Yoshie Shimoyama |
Department of Pathology and Clinical Laboratories, Nagoya University Hospital |
| Author |
Tsuneya Nakamura |
Department of Endoscopy, Aichi Cancer Center Hospital |
| Author |
Shigeo Nakamura |
Department of Pathology and Clinical Laboratories, Nagoya University Hospital |
| [ Summary ] |
Malignant lymphoma arising in digestive organs includes a number of disease entities. They are generally characterized by their distinct biologic properties, and are sometimes associated with infectious agents (e. g., Helicobacter pylori, Campylobacter jejuni, hepatitis C virus, Epstein-Barr virus, and human T-cell leukemia virus type I ). Lesions (e. g., coeliac disease) may contribute to the pathogenesis of GI tract lymphoma. Moreover, malignant lymphoma, which is eventually found in digestive organs, may represent secondary involvement of systemic diseases. Recently, the number of immunodeficiency-associated lymphoproliferative disorders also appears to be increasing. This vast spectrum or heterogeneity existing in malignant lymphoma, affecting the digestive organs, often poses diagnostic and therapeutic problems for pathologists and clinicians. Lympboma entities are concisely summarized according WHO classifications with special reference to their anatomical sites, especially in the digestive organs. |