臨牀消化器内科 Vol.22 No.10(1)


特集名 消化器臨床医のための病理学 -- 特殊染色を含めて
題名 消化器腫瘍の病理診断における特殊染色・免疫染色の有用性 -- その基礎と応用
発刊年月 2007年 09月
著者 加藤 洋 獨協医科大学日光医療センター病理部/癌研究会癌研究所病理部
著者 山本 智理子 癌研究会癌研究所病理部
著者 鹿取 正道 癌研究会癌研究所病理部
【 要旨 】 消化器の日常腫瘍診断における特殊染色・免疫染色の有用性に関して,その基礎と応用を概括した.基礎としては,腫瘍の種類をよく知ること,特殊染色および免疫染色の特徴を知ることが肝要である.腫瘍分類の実際,染色の原理・技術,抗体の種類などは成書に譲った.これら染色が関わるであろう,臨床的あるいは組織学的問題点 (腫瘍の存在診,鑑別診断,悪性度診断など)をまとめた.応用では,問題点の解決のためにこれら染色がどのように応用されるかを,いくつかの問題に絞り実例を挙げて示した.
Theme Guidebook of Pathology for Gastroenterologists and Hepatologists ; Including Special Stains and Immunohistochemistry
Title Utility of Special Staining and Immunostainings for Histological Diagnosis of Digestive Organ Tumors ; Its Base and Application
Author Yo Kato Department of Pathology, Nikko Medical Center, Dokkyo Medical University / Department of Pathology, the Cancer Institute, Japanese Foundation for Cancer Research
Author Noriko Yamamoto Department of Pathology, the Cancer Institute, Japanese Foundation for Cancer Research
Author Masamichi Katori Department of Pathology, the Cancer Institute, Japanese Foundation for Cancer Research
[ Summary ] The utility of special staining and immuno-staining for routine histological examinations of digestive organ tumors (DOTs) is reviewed. A general knowledge of various types of DOTs (classification) and the meanings of each special or immuno-staining are also examined. The actual classification of DOTs, the principles and techniques of staining, and the lists of antibodies were omitted, due to lack of space. Problems (such as presence or absence of tumors, differential diagnoses, searches of primary sites, low grade or high grade malignancy of tumors etc.) which may be encountered in routine examinations and may help solve the question of which staining mode to use. The usefulness of special and / or immuno-staining in solving problems, is illustrated by showing several practical cases along with practical solutions for the above problems.
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