| Theme |
Barrett's Esophagus |
| Title |
Chromoendoscopy and Dynamic Chemical Endoscopy Using Acetic Acid in Barrett's Esophagus and Esophageal Adenocarcinoma |
| Author |
Kazuyoshi Yagi |
Department of Internal Medicine, Niigata Prefectural Yoshida Hospital |
| Author |
Jun Watanabe |
Department of Internal Medicine, Niigata Prefectural Yoshida Hospital |
| Author |
Atsuo Nakamura |
Department of Internal Medicine, Niigata Prefectural Yoshida Hospital |
| Author |
Atsuo Sekine |
Department of Internal Medicine, Niigata Prefectural Yoshida Hospital |
| [ Summary ] |
Methylene blue, crystalviolet, indigocarmin and acetic acid have been used in the chromoendoscopy of Barrett's esophagus. Methylene blue is used for detection of intestinal metaplasia and all types of columnar epithelium are stained with crystalviolet. Indigocarmin is used to enhance uneven mucosa. There are two purposes for using acetic acid in the diagnosis of Barrett's esophagus. The first is to whiten the epithelium which is observed with magnifying endoscopy. The second is to create a contrast between the cancerous epithelium and the non-cancerous epithelium because aceto-whitening of the cancerous epithelium will disappear more quickly than will the non-cancerous epithelium. Methylene blue and crystalviolet are used for staining methods and indigocarmin is used for contrast methods. Acetic acid method produces a chemical reaction. |