Theme |
Barrett's Esophagus |
Title |
Historical and Current Concepts Concerning Barrett's Esophagus |
Author |
Tatsuyuki Kawano |
Department of Surgery, Tokyo Medical and Dental University Hospital |
Author |
Kazuo Ogiya |
Department of Surgery, Tokyo Medical and Dental University Hospital |
Author |
Shigeo Haruki |
Department of Surgery, Tokyo Medical and Dental University Hospital |
Author |
Koji Tanaka |
Department of Surgery, Tokyo Medical and Dental University Hospital |
Author |
Kenro Kawada |
Department of Surgery, Tokyo Medical and Dental University Hospital |
Author |
Yasuaki Nakajima |
Department of Surgery, Tokyo Medical and Dental University Hospital |
Author |
Tetsuro Nishikage |
Department of Surgery, Tokyo Medical and Dental University Hospital |
Author |
Kagami Nagai |
Department of Surgery, Tokyo Medical and Dental University Hospital |
[ Summary ] |
Norman Barrett originally described two special conditions, namely a congenital short esophagus with an intrathoracic gastric columnar lining and congenitally gastric heterotropia in those esophagus with ulceration. Later those conditions were termed “Barrett”. This is an acquired condition with esophageal columnar metaplasia following chronic gastro-esophageal reflux. Typical cases of Barrett's esophagus are defined as those having circumferential columnar metaplasia with minimal spreading (3 cm or more) from the esophago-gastric junction because precise recognition of EGJ is difficult. Recently, from the view point of adeno-carcinogenesis of the esophagus, the term and concept of the short-segment Barrett's esophagus as a developing condition of the classical Barrett's esophagus and the confirmation of intestinal metaplasia have been required. However, the definition of Barrett's esophagus is still controversial. |