臨牀消化器内科 Vol.21 No.9(4-1)


特集名 内視鏡的粘膜下層剥離術 (ESD) のトレーニングとリスクマネージメント
題名 ESD習得後に必要とされる基本事項 (1) 上部消化管ESDにおける周術期使用薬剤の取り扱いと全身麻酔下ESD
発刊年月 2006年 08月
著者 佐藤 嘉高 昭和大学横浜市北部病院消化器センター
著者 井上 晴洋 昭和大学横浜市北部病院消化器センター
著者 加賀 まこと 昭和大学横浜市北部病院消化器センター
著者 林 武雅 昭和大学横浜市北部病院消化器センター
著者 里舘 均 昭和大学横浜市北部病院消化器センター
著者 工藤 進英 昭和大学横浜市北部病院消化器センター
【 要旨 】 当院での上部消化管内視鏡的粘膜下層剥離術 (ESD) の際の抗血栓薬の取り扱い,鎮痙薬,sedationの使用について述べる.ESDは従来法に比べて手技的に難易度が高いことが多く,重篤な偶発症を引き起こす可能性があり,この対策として当院では2時間以上を要すると見込んだESDは手術室での全身麻酔下で行うことを一般化している.全身麻酔下ESDのメリットは多く,長時間を要する困難症例や,ESD初級者にとってはとくに有効な手段と考えられる.また,全身麻酔下ESDは穿孔時に起きる縦隔気腫,気胸を軽減させる可能性があるのではないかと思われた.
Theme Training System and Risk Management for Endoscopic Submucosal Dissection (ESD)
Title Peri-therapeutic Treatment and Advantage of General Anesthesia for Endoscopic Submucosal Dissection (ESD) Cases
Author Yoshitaka Sato Digestive Disease Center, Showa University Northern Yokohama Hospital
Author Haruhiro Inoue Digestive Disease Center, Showa University Northern Yokohama Hospital
Author Makoto Kaga Digestive Disease Center, Showa University Northern Yokohama Hospital
Author Takemasa Hayashi Digestive Disease Center, Showa University Northern Yokohama Hospital
Author Hitoshi Satodate Digestive Disease Center, Showa University Northern Yokohama Hospital
Author Shin-ei Kudo Digestive Disease Center, Showa University Northern Yokohama Hospital
[ Summary ] Similar, positive views were held by all contributing to this report on ESD modalities. A antithrombotic drugs should be withdrawn preoperatively to decrease hemorrhagic risk. However, care should be taken to avoid thromboembolisms in the withdrawl period. Therefore, we find varied opinions by medical specialists concerning correct drug withdrawal periods. Sedation of the patient should be by intravenous injection of diazepam (5-10 mg / body) and pethidine hydrochloride (35 mg / body). However, it is difficult to maintain appropriate sedative states when ESD is performed over an extended period. Because of this, patients being operated on for over two hours should receive general anesthesia. General anesthesia was used in 92 ESD cases, from November, 2002 to March, 2006. There were no complications reported with patients receiving general anesthesia. There are many merits in using general anesthesia during ESD. The use of general anesthesia is considered safe even in ESD cases which are difficult. Intraoperative incidents seemed to decrease when ESD was performed using general anesthesia.
戻る