特集名 | E型肝炎 -- 最新の知見 | |
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題名 | 人獣共通感染症としてのE型肝炎 (2) イノシシにおけるE型肝炎ウイルス感染 | |
発刊年月 | 2006年 05月 | |
著者 | 道堯 浩二郎 | 愛媛大学医学部光学医療診療部 |
著者 | 堀池 典生 | 愛媛大学医学部第三内科 |
【 要旨 】 | E型肝炎ウィルス (HEV) は人獣共通感染症で,ブタ,イノシシ,シカに感染が確認されている.本邦の海外渡航歴のないE型肝炎例のうち,イノシシ肉や内臓を食した後に発症したE型肝炎例が散見され,イノシシ肉 (内臓) からの経口感染はHEVの重要な感染経路と考えられる.発症例は中高年の男に多い.本州,九州,四国でHEV-RNA陽性のイノシシが証明され,どの地方でもイノシシ肉や内臓の生食はHEV感染の危険があると考えられる.また,急性肝炎診察時には野生動物の肉,内臓の摂取歴を聞く習慣をつけることが重要である. |
Theme | Update on Hepatitis E | |
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Title | Hepatitis E as a Zoonotic Disease : Hepatitis E Virus Infection among Wild Boars | |
Author | Kojiro Michitaka | Endoscopy Center, Ehime University School of Medicine |
Author | Norio Horiike | Third Department of Internal Medicine, Ehime University School of Medicine |
[ Summary ] | Zoonotic transmission of the hepatitis E virus (HEV) has been reported. The significance of wild boars as a source of HEV infection was reviewed. The number of Japanese patients with acute hepatitis E, including fulminant hepatitis who had a history of eating wild boar meat, including liver, has totaled four. Several investigators have studied the prevalence of anti-HEV and HEV-RNA in wild boars, and found that HEV-RNA was present in several % of wild boars. Boars positive for HEV-RNA were found in the Kyushu, Shikoku and Honshu areas in Japan. From these reports, wild boars have been identified as an important source of zoonotic HEV transmission. |