臨牀消化器内科 Vol.21 No.2(4-1)


特集名 膵管内乳頭粘液性腫瘍 (IPMT ; intraductal papillary-mucinous tumor)
題名 診断 (1) 診断の手順
発刊年月 2006年 02月
著者 鈴木 裕 杏林大学医学部外科
著者 阿部 展次 杏林大学医学部外科
著者 森 俊幸 杏林大学医学部外科
著者 杉山 政則 杏林大学医学部外科
著者 跡見 裕 杏林大学医学部外科
【 要旨 】 膵管内乳頭粘液性腫瘍 (IPMT) の病態は多量の粘液による膵管拡張を主体とし,壁在結節を認めることがあるため,これらを明瞭に描出しうる検査が有用である.侵襲度の低いUS, CTはスクリーニング検査として有用であり,これらにて膵管拡張を描出し,MRCP, ERCP, EUS, IDUSなどで診断確定と他疾患との鑑別のための精査を行う.IPMTはslow growingであり,腺腫は経過観察可能である場合がある.全国症例調査の結果では高齢,有症状,高い粘液分泌能,主膵管型・複合型,著明な膵管拡張,大きな壁在結節などが腺癌の予測因子として有用であり,拡張膵管の描出に優れるEUSなどを治療方針決定のために採用すべきである.
Theme IPMT ; Intraductal Papillary-Mucinous Tumor
Title Diagnosis of Intraductal Papillary-Mucinous Tumor
Author Yutaka Suzuki Department of Surgery, Kyorin University School of Medicine
Author Nobutsugu Abe Department of Surgery, Kyorin University School of Medicine
Author Toshiyuki Mori Department of Surgery, Kyorin University School of Medicine
Author Masanori Sugiyama Department of Surgery, Kyorin University School of Medicine
Author Yutaka Atomi Department of Surgery, Kyorin University School of Medicine
[ Summary ] There has not been an increased consensus on the proper treatment of intraductal papillary-mucinous tumors (IPMT). It is important to select the appropriate diagnostic techniques. Because of abundant mucous secretion, the pancreatic duct is dilated and the mural nodule is located in the pancreatic duct. Diagnostic images that can detect these findings are useful. US and CT are non-invasive and useful for screening MRCP, ERCP, EUS and IDUS are performed to confirm the diagnosis. Differential detection of pancreatic ductal dilatation indicates, a need for detailed examination with CT, ERCP, EUS or IDUS, to provide a diagnosis after detection of pancreatic ductal dilatation. IPMT develops slowly and benign IPMT may be followed up without surgery. Differentiation between benign and malignant tumors is important for appropriate treatment. MRCP is exellent in detecting dilated pancreatic ducts, and EUS in the mural nodule. These imaging modalities are were useful for decisions on treatment strategies.
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