臨牀消化器内科 Vol.20 No.10(3)


特集名 直腸・肛門病変をめぐる諸問題
題名 腸管子宮内膜症 -- 診断と治療
発刊年月 2005年 09月
著者 山形 和史 弘前大学医学部第一内科
著者 石黒 陽 弘前大学医学部第一内科
著者 蝦名 佐都子 弘前大学医学部第一内科
著者 島谷 孝司 弘前大学医学部第一内科
著者 平賀 寛人 弘前大学医学部第一内科
著者 棟方 昭博 弘前大学医学部第一内科
【 要旨 】 子宮内膜症は,異所性に子宮内膜組織が増殖する非腫瘍性疾患である.腸管子宮内膜症とは,腸管子宮内膜組織が腸管壁に増殖した状態であり,消化管出血,腸管の狭窄などの重篤な症状を合併することが問題となる.その形態からX線,内視鏡検査において炎症性腸疾患,悪性腫瘍との鑑別診断に苦慮する症例が多い.発生頻度は高くはないものの鑑別診断の片隅におくべき疾患である.腸管子宮内膜症は,子宮内膜症の病期が進行した状態であると考えられる.したがって本症の確定診断が得られ,腸管の高度の狭窄症状が認められた場合には外科的治療が主体となる.消化器内科医としては本症の確定診断を導くことが重要であり,腹痛・下血などの症状に加えて痛みの性状について十分な問診をし,本症を鑑別診断の一つとして考え,画像診断を速やかに行う必要がある.
Theme Current Topics on Anorectal Disorders
Title Intestinal Endometriosis
Author Kazufumi Yamagata First Department of Internal Medicine, Hirosaki University School of Medicine
Author Yoh Ishiguro First Department of Internal Medicine, Hirosaki University School of Medicine
Author Satoko Ebina First Department of Internal Medicine, Hirosaki University School of Medicine
Author Koji Shimaya First Department of Internal Medicine, Hirosaki University School of Medicine
Author Hiroto Hiraga First Department of Internal Medicine, Hirosaki University School of Medicine
Author Akihiro Munakata First Department of Internal Medicine, Hirosaki University School of Medicine
[ Summary ] The gastrointestinal tract is the most common site of extrapelvic endometriosis, with the sigmoid colon, descending colon, and rectum representing the areas most commonly involved. Rectovaginal septum with rectosigmoid involvement is thought to be the most common form of extrapelvic endometriosis. These lesions may be present with intestinal obstructions or symptoms such as pain, distension, diarrhea, constipation, or rectal bleeding. They also may be incidental findings at the time of laparoscopy.
Endometriosis can be determined from the history, pelvic examination, and ancillary tests. Endometriosis is classically defined as the presence of endometrial tissue (specifically, endometrial glands and stroma) outside the uterine cavity. It is still argued that diagnosis can be made visually and does not need pathologic confirmation. It is suggested that characteristic signs and symptoms are helpful in diagnosing in gastrointestinal endometriosis. When rectovaginal or uterosacral ligament involvement is noted, the pain is often referred to the rectum or lower back. Pain radiating down the leg may also be seen. The pain may progress and begin prior to the onset of menses or become chronic and be noted throughout most of the menstrual cycle in conjunction with the rectal bleeding. Colonoscopy and double-contrast barium examination is useful to define gastrointestinal involvement. Treatment is dependent on symptoms, extent of disease, location, and degree of bowel dysfunction. Neoplastic changes in endometriosis of the bowel are very rare.
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