| Theme |
H.pylori Negative Upper Gastroenterological Diseases; Increasing of Their Incidence in the 21st Century |
| Title |
NSAID-induced Gastric Ulcers |
| Author |
Shinichi Ota |
Department of Gastroenterology and Hepatology, Saitama Medical School |
| Author |
Shin Arai |
Department of Gastroenterology and Hepatology, Saitama Medical School |
| Author |
Yukinori Imai |
Department of Gastroenterology and Hepatology, Saitama Medical School |
| Author |
Hiromi Bamba |
Saitama Medical Center, Saitama Medical School |
| [ Summary ] |
The long term use of NSAID has been shown to frequently induce gastric ulcers in Japan. With NSAIDs, upper gastro intestinal bleeding, induced by aspirin, may increase in the future, According to EBM-based guidelines for the management of gastric ulcers. These guidelines revealed that co-administration of prostaglandin and protonpump inhibitors were recommended for the reduction of NSAID related ulcers. |