臨牀消化器内科 Vol.17 No.8(9)


特集名 内視鏡の偶発症とその対策
題名 EIS,EVLの偶発症と対策
発刊年月 2002年 07月
著者 宮本 安尚 久留米大学第二内科/消化器病センター
著者 於保 和彦 久留米大学第二内科/消化器病センター
著者 坂本 慶博 久留米大学第二内科/消化器病センター
著者 境 研二 久留米大学第二内科/消化器病センター
著者 熊本 正史 久留米大学第二内科/消化器病センター
著者 田山 千鶴 久留米大学第二内科/消化器病センター
著者 豊永 純 久留米大学第二内科/消化器病センター
【 要旨 】 本邦では食道・胃静脈瘤に対する認識が高く,静脈瘤の内視鏡治療が広く行われており,門脈圧亢進症を有する患者の予後の向上につながっている.EISはEVLに比し偶発症が多く,使用する硬化剤に伴う血栓症や腎不全のほか,穿刺部位からの出血や穿孔など重篤なものがある.またEISによる食道狭窄は患者のQOLを低下させる.一方,EVLにはオーバーチューブの使用による咽頭・食道の穿孔や損傷などEVL特有の偶発症がある.偶発症の予防には,患者リスクの評価のほか,門脈血行動態の術前把握が必要不可欠である.とくにpipe-line varix,胃穹窿部静脈瘤,A-P shunt,門脈腫瘍塞栓,PPVAの合併などに注意する.緊急出血例は止血を第一目標とし,追加治療は全身状態改善後に行う.待期・予防例では,低侵襲で効果の永続が期待できる治療方法を選択すべきである.
Theme Complications and their Managements for Gastrointestinal Endoscopy
Title Complications of EIS and EVL, and their Managements
Author Yasunao Miyamoto The Second Department of Internal Medicine, Division of Gastroenterology and Endoscopy, Kurume University
Author Kazuhiko Oho The Second Department of Internal Medicine, Division of Gastroenterology and Endoscopy, Kurume University
Author Yoshihiro Sakamoto The Second Department of Internal Medicine, Division of Gastroenterology and Endoscopy, Kurume University
Author Kenji Sakai The Second Department of Internal Medicine, Division of Gastroenterology and Endoscopy, Kurume University
Author Masafumi Kumamoto The Second Department of Internal Medicine, Division of Gastroenterology and Endoscopy, Kurume University
Author Chizuru Tayama The Second Department of Internal Medicine, Division of Gastroenterology and Endoscopy, Kurume University
Author Atsushi Toyonaga The Second Department of Internal Medicine, Division of Gastroenterology and Endoscopy, Kurume University
[ Summary ] In Japan, the incidence of esophageal and gastric varices is high and endoscopic treatment is widely performed. This has improved the prognosis for patients with portal hypertension. There are more complications with endoscopic injection sclerotherapy (EIS) compared to endoscopic variceal ligation (EVL). Furthermore, those complications are often serious, such as bleeding or perforation of a puncture site, along with thrombosis and renal insufficiency caused by sclerosant. Moreover, strictures in the esophagus, related to EIS, reduce the patient's QOL. On the other hand, there are peculiar complications in EVL, such as perforation or injury to the pharynx and esophagus, related to overtube insertion. For prevention of these complications, it is important to evaluate the patient's condition and portal hemodynamics before the treatment. Caution is especially necessary for the diagnosis of pipe-line varix, solitary fundal varices, A-P shunts, portal vein tumor thrombosis, and porto-pulmonary venous anastomosis. In cases of heavy bleeding from varices, achievement of hemostasis is the primary goal. Additional treatment should be performed following improvements in the patient's general condition. In elective and the prophylactic treatment, we should choose the treatment option thought to have the lowest risk and the greatest expected permanent effect.
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