| Theme |
Lesions of Esophagogastric Junction -- Its Diagnostic and Therapeutic Strategies |
| Title |
Lesions in the Gastroesophageal Junction -- Barrett's Esophagus |
| Author |
Teruo Kouzu |
Department of Endoscopic Diagnostics and Therapeutics, Chiba University School of Medicine |
| Author |
Etsuo Hishikawa |
Department of Endoscopic Diagnostics and Therapeutics, Chiba University School of Medicine |
| Author |
Yukika Ishikawa |
Department of Endoscopic Diagnostics and Therapeutics, Chiba University School of Medicine |
| Author |
Seiji Yoshimura |
Department of Endoscopic Diagnostics and Therapeutics, Chiba University School of Medicine |
| Author |
Shinichi Miyazaki |
Department of Endoscopic Diagnostics and Therapeutics, Chiba University School of Medicine |
| Author |
Yasuo Suzuki |
Department of Endoscopic Diagnostics and Therapeutics, Chiba University School of Medicine |
| [ Summary ] |
Currently, the condition in which the esophageal mucosa is replaced by a columnar epithelium is generally called Barrett's esophagus (BE) or Barrett's epithelium. One of the sources for questions about this disease is its biological characteristics. In other words, BE is considered to have the type of mucosa that may frequently become a carcinogenic base. In addition, questions remain as to the diagnostic definition, and pathogenesis of this disease. The main reason for these questions is how do we identify the gastroesophageal junction. Our opinions on the disappearing portion of the rugae, which has crept from the stomach, color differences, and longitudinal blood vessels, which are the same as those for the anal boundary. From this standpoint, we discussed a management method for BE by introducing 2 cases of Barrett's carcinoma developed in a short segment of BE (SSBE). We also reported on time-lapse changes in BE, and our experiences with changes in the molecularbiological characteristics of BE. |