臨牀消化器内科 Vol.17 No.4(3)


特集名 食道胃接合部の病変 -- 診断と治療方針を中心に
題名 食道アカラシア
発刊年月 2002年 04月
著者 小澤 壯治 慶應義塾大学医学部外科
著者 北川 雄光 慶應義塾大学医学部外科
著者 中村 榮一 慶應義塾大学医学部外科
著者 北島 政樹 慶應義塾大学医学部外科
【 要旨 】 食道アカラシアは食道疾患研究会により,「下部食道噴門部の弛緩不全による食物の通過障害や,食道の異常拡張などがみられる機能的疾患」と定義され,迷走神経系の異常によって起こる食道の運動機能異常疾患である.診断には症状の聴取,食道造影検査,内視鏡検査,食道内圧測定などが必要である.治療は,薬物療法,ボツリヌス毒素注入療法,拡張術,手術の四つに分けられるが,障害された食道運動機能を完全に回復させるものではなく,食道の通過状態の改善をはかることを目的としている.なかでも腹腔鏡下 Heller and Dor法は高い治療効果と低侵襲性の観点から現在の標準術式として妥当であり,今後はその低侵襲性の特徴を生かして手術適応が拡大するものと期待される.
Theme Lesions of Esophagogastric Junction -- Its Diagnostic and Therapeutic Strategies
Title Achalasia of the Esophagus
Author Soji Ozawa Department of Surgery, School of Medicine, Keio University
Author Yuko Kitagawa Department of Surgery, School of Medicine, Keio University
Author Eiichi Nakamura Department of Surgery, School of Medicine, Keio University
Author asaki Kitajima Department of Surgery, School of Medicine, Keio University
[ Summary ] Achalasia is a motor disorder of the esophagus characterized by loss of esophageal peristalsis and failure of the lower esophageal sphincter (LES) to completely relax upon deglutition. For the diagnosis of achalasia, symptoms such as dysphagia should be evaluated and esophagograms, endoscopy, or manometric studies should be performed. There are four methods of treatment, the first is medical therapy, the second is botulinum toxin injection therapy, the third is pneumatic dilatation, and the fourth is surgery. Recently, laparoscopic Heller myotomy and Dor fundoplication (Heller and Dor operations) have been thought to be the operation of first choice. As Csendes et al. reported; surgical treatment was better than pneumatic dilatation and as laparoscopic surgery is less invasive, the indications for laparoscopic Heller and Dor operations can include all achalasia patients, except those patients who respond to medical therapy, patients who will not accept operations, or patients who can not tolerate an operation because of poor overall condition. We successfully performed laparoscopic Heller and Dor operations on 35 patients and the postoperative courses were all uneventful. Surgeons considering surgical procedures, should know that laparoscopic Heller and Dor operations are an ideal, minimally invasive treatment for esophageal achalasia.
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