| Theme |
Chemotherapy for Gastrointestinal Malignancy |
| Title |
Tumor Dormancy by Anti-Angiogenesis |
| Author |
Yutaka Takahashi |
Department of Surgical Oncology, Cancer Research Institute, Kanazawa University |
| Author |
Masayoshi Mai |
Department of Surgical Oncology, Cancer Research Institute, Kanazawa University |
| [ Summary ] |
Clinical trials of anti-angiogenetic drugs, such as anti vascular endothelial cell growth factor (VEGF) antibody, inhibitor of VEGF receptor tyrosine kinase, are in phase II/III studies in the United States and Europe. In this paper, we introduced data concerning these drugs in relation to colorectal cancer and discussed strategies related to anti-angiogenesis, not associated with tumor atrophy, but to tumor dormancy. |