| Theme |
Gastroenterological Diseases and Therapy with Transplantation |
| Title |
Long Term Complications after Liver Transplantation |
| Author |
Hiroyuki Furukawa |
Organ Transplantation and Regenerative Medicine, Hokkaido University School of Medicine |
| Author |
Tsuyoshi Shimamura |
Gastroenterological Surgery and General Surgery, Hokkaido University School of Medicine |
| Author |
Maeng Bong Jin |
Organ Transplantation and Regenerative Medicine, Hokkaido University School of Medicine |
| Author |
Toshikana Kamiyama |
Gastroenterological Surgery and General Surgery, Hokkaido University School of Medicine |
| Author |
Michiaki Matsushita |
Gastroenterological Surgery and General Surgery, Hokkaido University School of Medicine |
| Author |
Satoru Todo |
Gastroenterological Surgery and General Surgery, Hokkaido University School of Medicine |
| [ Summary ] |
The outcome of liver transplantation, either using living or cadaver donors, has significantly improved. The five year survival rate has reached 75% to 80%. However, there still remain many problems to be solved. Although the short-term complications are well known, little is known about the long-term complications. Therefore, the long-term complications were presented in this chapter; 1) technical complications such as hepatic artery thrombosis, hepatic vein thrombosis, and biliary stricture, 2) immunologic complication such as chronic rejection, 3) adverse effects of immunosuppressive agents such as renal dysfunction, hypertension, diabetes, neurologic disorders, obesity, and hypercholesterolemia. |