| Theme |
Endoscopic Diagnosis of Helicobater pylori Infection |
| Title |
Characteristics of Gastric Mucosa in Patients with Gastric Cancer |
| Author |
Naomi Uemura |
Department of Gastroenterology, Kure Kyosai Hospital |
| Author |
Shiro Okamoto |
Department of Gastroenterology, Kure Kyosai Hospital |
| Author |
Soichiro Yamamoto |
Department of Gastroenterology, Kure Kyosai Hospital |
| [ Summary ] |
Our previous study results suggest that the development of both types of gastric cancer is caused by H.pylori-associated gastritis, and the risk for development of gastric cancer in H.pylori-negative subjects is extremely low. Subjects having H.pylori-positive gastric mucosa with severe atrophy and/or corpus gastritis may be at a particularly high risk for gastric cancer.
The enlarged fold and the adhesion of the mucus in the gastric body are endoscopically observed with the reflection of atrophic changes in the gastric mucosa and a decrease in gastric acid secretion. In endoscopic examinations, detailed observation should be made of these high-risk groups. It has been reported that the normalization of enlarged folds and the desappearance of adhesion mucus from the gastric body is associated with the possibility of suppressing the development of metachronous gastric cancer through H.pylori eradication after EMR. Therefore, detailed examination, along with extended eradication treatment should be considered to be a necessity in future treatments. |