臨牀消化器内科 Vol.15 No.5(7-2)


特集名 門脈圧亢進症
題名 食道・胃静脈瘤の治療 (2) 内視鏡治療 -- EIS, EVL
発刊年月 2000年 05月
著者 小原 勝敏 福島県立医科大学医学部第二内科
【 要旨 】 静脈瘤治療に大きく貢献した内視鏡治療はEOによる硬化療法(EIS)に始まり,各種治療薬剤(EO,AS,ET,cyanoacrylateなど)を用いた治療手技が次から次へと展開された.一方,薬剤を使用しない内視鏡治療として静脈瘤結紮術(EVL)が導入され,静脈瘤治療は新たな展開を迎えた.いまや,静脈瘤治療は多様化し,病態に応じた適切な治療法を選択できるようになった.したがって,静脈瘤治療は安全かつ効果的で,患者のQOLの向上が得られる手技であることが要求される.そのためには,一つの手技に固執することなく,患者の全身状態や肝障害の程度,そして門脈血行動態に応じた適切な治療法の選択と併用が重要である.
Theme Portal Hypertension
Title Endoscopic Treatment for Esophageal and Gastric Varices -- EIS and EVL
Author Katsutoshi Obara Internal Medicine II, Fukushima Medical University School of Medicine
[ Summary ] In the endoscopic treatment of varices, which represents a great advance, endoscopic injection sclerotherapy (EIS) was initially performed using ethanolamineoleate (EO), and was followed by the development of other methods with various other drugs [e.g., EO, aethoxysklerol (AS), ethanol (ET) and cyanoacrylate]. With respect to endoscopic treatment not involving the use of any drugs, endoscopic variceal ligation (EVL) has been introduced and represents a new advance in the treatment of varices. Nowadays, an appropriate treatment method can be selected from among the array of treatment methods available for the treatment of varices depending on the patient's condition. Therefore, the requirements for the treatment method of varices include not only the safety and efficacy of the procedure but also improvement in the quality of life (QOL) of the patient. For this purpose, instead of persisting with one particular method, it is important to choose and combine the appropriate treatment methods depending on the patient's physical condition, the severity of hepatic dysfunction and the portal circulation.
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