臨牀消化器内科 Vol.15 No.12(3)


特集名 大腸癌 -- 最新の進行大腸癌治療戦略
題名 低侵襲性治療 -- 腹腔鏡下大腸切除術の適応と限界
発刊年月 2000年 11月
著者 長谷川 博俊 慶應義塾大学医学部外科
著者 渡邊 昌彦 慶應義塾大学医学部外科
著者 北島 政樹 慶應義塾大学医学部外科
【 要旨 】 1992年から現在までの8年間に大腸癌患者327例(Dukes A:245例,B:38例,C:39例,D:5例)に対し腹腔鏡下大腸切除術を施行した.術後観察期間中央値は37カ月(1~97カ月)であった.治癒切除322例中8例に再発を認めた.このうち腹膜再発を認めた4例の深達度はss:1例,se:2例,si:1例であった.Kaplan-Meier法による5年無再発生存率はDukes A:97.4%,B:95.2%(4年無再発生存率),C:81.5%であり,5年全生存率はDukes A:99.3%,B:100%(4年全生存率), C:96.0%であった.早期大腸癌に対する腹腔鏡下手術の長期予後は良好で,本法のよい適応であると思われた.mp癌の予後も比較的良好であったが,ss以深の進行癌に対しては慎重な経過観察が必要である.
Theme Up-to-date Therapuetic Strategy for Advanced Colorectal Cancer
Title Indications and the Limit of Laparoscopic Colectomy for Colorectal Cancer
Author Hirotoshi Hasegawa Department of Surgery, Keio University School of Medicine
Author Masahiko Watanabe Department of Surgery, Keio University School of Medicine
Author Masaki Kitajima Department of Surgery, Keio University School of Medicine
[ Summary ] During the past 8 years, 327 patients with colorectal cancer (Dukes A:245, B:38, C:39, D:5) underwent laparoscopic colectomy. The median follow-up period was 37 months (1-97months). In 322 curative cases 8 patients had recurrences. Of these, 3 patients with pT3 tumours, and 1 with a pT4, had peritoneal recurrences. The 5 year disease-free survival rates, using the Kaplan-Meier method, were 97.4% for Dukes A, 95.2% for Dukes B and 81.5% for Dukes C. The 5 year overall survival rates were 99.3% for Dukes A, 100% for Dukes B and 96.0% for Dukes C. The long-term results of laparoscopic surgery, in patients with early color ectal cancer, were favourable, whereas strict follow ups are necessary in patients with pT3 tumours.
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